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SIRT2 sirtuin 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 100425019, updated on 8-Mar-2024

Summary

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Official Symbol
SIRT2provided by VGNC
Official Full Name
sirtuin 2provided by VGNC
Primary source
VGNC:VGNC:77219
See related
Ensembl:ENSMMUG00000023640
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See SIRT2 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
17
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (38125682..38151603, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (34614095..34640069, complement)

Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein L Neighboring gene Ras and Rab interactor like Neighboring gene NFKB inhibitor beta Neighboring gene coiled-coil glutamate rich protein 2 Neighboring gene seryl-tRNA synthetase 2, mitochondrial Neighboring gene mitochondrial ribosomal protein S12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NAD-dependent histone deacetylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NAD-dependent protein deacetylase sirtuin-2
Names
NAD-dependent deacetylase sirtuin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041772.1 Reference Mmul_10 Primary Assembly

    Range
    38125682..38151603 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015123871.2 → XP_014979357.1  NAD-dependent protein deacetylase sirtuin-2 isoform X1

    UniProtKB/TrEMBL
    H9FRI7, H9YXU3
    Related
    ENSMMUP00000078053.1, ENSMMUT00000086282.1
    Conserved Domains (1) summary
    cd01408
    Location:77 → 331
    SIRT1; SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 ...

  2. XM_015123872.2 → XP_014979358.1  NAD-dependent protein deacetylase sirtuin-2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5QNQ0, A0A1D5QW78, F7H1P3, F7H1P7, F7H1P9, H9FRI7
    Related
    ENSMMUP00000052308.1, ENSMMUT00000072478.2
    Conserved Domains (1) summary
    cd01408
    Location:40 → 294
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...

  3. XM_028838943.1 → XP_028694776.1  NAD-dependent protein deacetylase sirtuin-2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5QNQ0, A0A1D5QW78, F7H1P3, F7H1P7, F7H1P9, H9FRI7
    Conserved Domains (1) summary
    cd01408
    Location:40 → 294
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...

  4. XM_028838942.1 → XP_028694775.1  NAD-dependent protein deacetylase sirtuin-2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5QNQ0, A0A1D5QW78, F7H1P3, F7H1P7, F7H1P9, H9FRI7
    Related
    ENSMMUP00000068753.1, ENSMMUT00000097858.1
    Conserved Domains (1) summary
    cd01408
    Location:40 → 294
    SIRT1; Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins ...

  5. XM_015123874.2 → XP_014979360.1  NAD-dependent protein deacetylase sirtuin-2 isoform X3

    UniProtKB/TrEMBL
    H9FRI7
    Related
    ENSMMUP00000055917.2, ENSMMUT00000072668.2
    Conserved Domains (1) summary
    cd01408
    Location:16 → 270
    SIRT1; SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 ...
Nucleotide Protein
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