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TOP1 DNA topoisomerase I [ Callithrix jacchus (white-tufted-ear marmoset) ]

Gene ID: 100397121, updated on 8-Mar-2024

Summary

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Gene symbol
TOP1
Gene description
DNA topoisomerase I
See related
Ensembl:ENSCJAG00000018101
Gene type
protein coding
RefSeq status
MODEL
Organism
Callithrix jacchus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix
Orthologs
human mouse all
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Genomic context

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See TOP1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2023_03 current mCalJa1.2.pat.X (GCF_011100555.1) 5 NC_071446.1 (34371873..34469601)
105 previous assembly Callithrix_jacchus_cj1700_1.1 (GCF_009663435.1) 5 NC_048387.1 (34280922..34378635)

Chromosome 5 - NC_071446.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC128932278 Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC118153601 Neighboring gene phospholipase C gamma 1 Neighboring gene zinc fingers and homeoboxes 3 Neighboring gene lipin 3 Neighboring gene elastin microfibril interfacer 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De novo assembly of the common marmoset transcriptome from NextGen mRNA sequences. Maudhoo MD, et al. Gigascience, 2014. PMID 25243066, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA topoisomerase type I (single strand cut, ATP-independent) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA topological change IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chromosome segregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA topoisomerase 1
Names
topoisomerase (DNA) I

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_011100555.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCalJa1.2.pat.X

Genomic

  1. NC_071446.1 Reference mCalJa1.2.pat.X

    Range
    34371873..34469601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002747564.5 → XP_002747610.1  DNA topoisomerase 1

    See identical proteins and their annotated locations for XP_002747610.1

    UniProtKB/TrEMBL
    F6STR2, F6SUM9
    Related
    ENSCJAP00000033567.1
    Conserved Domains (2) summary
    smart00435
    Location:362 → 739
    TOPEUc; DNA Topoisomerase I (eukaryota)
    cd03488
    Location:218 → 432
    Topoisomer_IB_N_htopoI_like; Topoisomer_IB_N_htopoI_like : N-terminal DNA binding fragment found in eukaryotic DNA topoisomerase (topo) IB proteins similar to the monomeric yeast and human topo I. Topo I enzymes are divided into: topo type IA (bacterial) and type IB (eukaryotic). ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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