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MKRN2 makorin ring finger protein 2 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100340148, updated on 6-Jun-2024

Summary

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Gene symbol
MKRN2
Gene description
makorin ring finger protein 2
See related
Ensembl:ENSOCUG00000014171
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 9 NC_067382.1 (104672460..104700860)

Chromosome 9 - NC_067382.1Genomic Context describing neighboring genes Neighboring gene tRNA splicing endonuclease subunit 2 Neighboring gene uncharacterized LOC103349184 Neighboring gene MKRN2 opposite strand Neighboring gene Raf-1 proto-oncogene, serine/threonine kinase Neighboring gene 39S ribosomal protein L42, mitochondrial-like Neighboring gene small nucleolar RNA SNORD5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067382.1 Chromosome 9 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase makorin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067382.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    104672460..104700860
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051851728.1 → XP_051707688.1  E3 ubiquitin-protein ligase makorin-2 isoform X5

    UniProtKB/TrEMBL
    A0A5F9CFM3, G1U3K8

  2. XM_051851726.1 → XP_051707686.1  E3 ubiquitin-protein ligase makorin-2 isoform X2

    UniProtKB/TrEMBL
    A0A5F9CFM3, A0A5F9DBC3

  3. XM_008260414.3 → XP_008258636.1  E3 ubiquitin-protein ligase makorin-2 isoform X4

    UniProtKB/TrEMBL
    A0A5F9CFM3, G1U3K8
    Related
    ENSOCUP00000023971.1
    Conserved Domains (3) summary
    smart00356
    Location:35 → 55
    ZnF_C3H1; zinc finger
    PHA03096
    Location:179 → 327
    PHA03096; p28-like protein; Provisional
    cd00162
    Location:238 → 292
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

  4. XM_008260413.3 → XP_008258635.1  E3 ubiquitin-protein ligase makorin-2 isoform X1

    UniProtKB/TrEMBL
    A0A5F9CFM3, A0A5F9DBC3
    Related
    ENSOCUP00000043133.1
    Conserved Domains (3) summary
    smart00356
    Location:44 → 64
    ZnF_C3H1; zinc finger
    PHA03096
    Location:188 → 336
    PHA03096; p28-like protein; Provisional
    cd00162
    Location:247 → 301
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

  5. XM_051851727.1 → XP_051707687.1  E3 ubiquitin-protein ligase makorin-2 isoform X3

    UniProtKB/TrEMBL
    A0A5F9CFM3

  6. XM_008260416.3 → XP_008258638.1  E3 ubiquitin-protein ligase makorin-2 isoform X3

    See identical proteins and their annotated locations for XP_008258638.1

    UniProtKB/TrEMBL
    A0A5F9CFM3
    Conserved Domains (3) summary
    smart00356
    Location:24 → 44
    ZnF_C3H1; zinc finger
    PHA03096
    Location:168 → 316
    PHA03096; p28-like protein; Provisional
    cd00162
    Location:227 → 281
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
Nucleotide Protein
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