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STAT1 signal transducer and activator of transcription 1 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100173683, updated on 11-Apr-2024

Summary

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Gene symbol
STAT1
Gene description
signal transducer and activator of transcription 1
Locus tag
CR201_G0007342
See related
Ensembl:ENSPPYG00000013027
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 11 NC_071996.2 (93931457..93976617, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) Unplaced Scaffold NW_026536879.1 (108059..153219, complement)

Chromosome 11 - NC_071996.2Genomic Context describing neighboring genes Neighboring gene NGFI-A binding protein 1 Neighboring gene glutaminase Neighboring gene ras-related protein Rab-1A-like Neighboring gene signal transducer and activator of transcription 4 Neighboring gene U6 spliceosomal RNA Neighboring gene putative high mobility group protein B1-like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • DKFZp459D206

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in type I interferon-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 1-alpha/beta
Names
signal transducer and activator of transcription 1, 91kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001133211.1 → NP_001126683.1  signal transducer and activator of transcription 1-alpha/beta

    See identical proteins and their annotated locations for NP_001126683.1

    Status: PROVISIONAL

    Source sequence(s)
    CR860763
    UniProtKB/TrEMBL
    A0A8I5TSX1, Q5R5U0
    Related
    ENSPPYP00000014555.3, ENSPPYT00000015144.3
    Conserved Domains (5) summary
    cd10372
    Location:557 → 707
    SH2_STAT1; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 1 proteins
    smart00964
    Location:2 → 121
    STAT_int; STAT protein, protein interaction domain
    pfam01017
    Location:139 → 315
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:317 → 566
    STAT_bind; STAT protein, DNA binding domain
    pfam12162
    Location:715 → 739
    STAT1_TAZ2bind; STAT1 TAZ2 binding domain

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071996.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    93931457..93976617 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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