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DLG4 discs large MAGUK scaffold protein 4 [ Bos taurus (cattle) ]

Gene ID: 100137840, updated on 8-Mar-2024

Summary

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Official Symbol
DLG4provided by VGNC
Official Full Name
discs large MAGUK scaffold protein 4provided by VGNC
Primary source
VGNC:VGNC:28086
See related
BGD:BT15847; Ensembl:ENSBTAG00000002564
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (26909163..26933445, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene asialoglycoprotein receptor 1 Neighboring gene small nucleolar RNA SNORA1 Neighboring gene acyl-CoA dehydrogenase very long chain Neighboring gene microRNA mir-324 Neighboring gene dishevelled segment polarity protein 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in AMPA glutamate receptor clustering IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in postsynaptic neurotransmitter receptor diffusion trapping IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disks large homolog 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191307.1 → NP_001178236.1  disks large homolog 4

    See identical proteins and their annotated locations for NP_001178236.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000019
    UniProtKB/TrEMBL
    F1MM66
    Related
    ENSBTAP00000003326.6, ENSBTAT00000003326.7
    Conserved Domains (6) summary
    cd12030
    Location:427 → 492
    SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
    smart00228
    Location:307 → 391
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    pfam00595
    Location:62 → 146
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam00625
    Location:530 → 708
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:242 → 309
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:10 → 61
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    26909163..26933445 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024979511.2 → XP_024835279.1  disks large homolog 4 isoform X7

    Conserved Domains (5) summary
    cd12030
    Location:370 → 435
    SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
    smart00228
    Location:250 → 334
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    pfam00595
    Location:5 → 89
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam00625
    Location:473 → 651
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:185 → 252
    PDZ_assoc; PDZ-associated domain of NMDA receptors

  2. XM_059877678.1 → XP_059733661.1  disks large homolog 4 isoform X7

  3. XM_059877677.1 → XP_059733660.1  disks large homolog 4 isoform X7

  4. XM_059877673.1 → XP_059733656.1  disks large homolog 4 isoform X2

    Related
    ENSBTAP00000103051.1, ENSBTAT00000131638.1

  5. XM_059877675.1 → XP_059733658.1  disks large homolog 4 isoform X5

  6. XM_024979508.2 → XP_024835276.1  disks large homolog 4 isoform X4

    Conserved Domains (6) summary
    cd12030
    Location:422 → 487
    SH3_DLG4; Src Homology 3 domain of Disks Large homolog 4
    smart00228
    Location:302 → 386
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    pfam00595
    Location:57 → 141
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam00625
    Location:525 → 703
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:237 → 304
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:6 → 56
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  7. XM_059877674.1 → XP_059733657.1  disks large homolog 4 isoform X3

  8. XM_024979507.2 → XP_024835275.2  disks large homolog 4 isoform X1

  9. XM_059877679.1 → XP_059733662.1  disks large homolog 4 isoform X7

  10. XM_059877676.1 → XP_059733659.1  disks large homolog 4 isoform X6

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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