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BIRC2 baculoviral IAP repeat containing 2 [ Equus caballus (horse) ]

Gene ID: 100061273, updated on 17-Aug-2024

Summary

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Official Symbol
BIRC2provided by VGNC
Official Full Name
baculoviral IAP repeat containing 2provided by VGNC
Primary source
VGNC:VGNC:15832
See related
Ensembl:ENSECAG00000012229
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See BIRC2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 7 NC_009150.3 (12798152..12820369)

Chromosome 7 - NC_009150.3Genomic Context describing neighboring genes Neighboring gene GTP-binding protein SAR1b pseudogene Neighboring gene baculoviral IAP repeat containing 3 Neighboring gene transmembrane protein 123 Neighboring gene 60S ribosomal protein L36 pseudogene Neighboring gene matrix metallopeptidase 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009150.3 Chromosome 7 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of necroptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
baculoviral IAP repeat-containing protein 2
Names
baculoviral IAP repeat-containing protein 2-like protein
baculoviral IAP repeat-containing protein-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009150.3 Reference EquCab3.0 Primary Assembly

    Range
    12798152..12820369
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023644711.1 → XP_023500479.1  baculoviral IAP repeat-containing protein 2

    UniProtKB/TrEMBL
    A0A5F5Q2M3, A0A9L0RHQ2
    Related
    ENSECAP00000063469.1, ENSECAT00000108691.1
    Conserved Domains (6) summary
    smart00238
    Location:249 → 317
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd00022
    Location:28 → 94
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd08329
    Location:434 → 525
    CARD_BIRC2_BIRC3; Caspase activation and recruitment domain found in Baculoviral IAP repeat-containing proteins, BIRC2 (c-IAP1) and BIRC3 (c-IAP2)
    cd14394
    Location:372 → 418
    UBA_BIRC2_3; UBA domain found in baculoviral IAP repeat-containing protein BIRC2, BIRC3 and similar proteins
    cd16713
    Location:546 → 599
    RING-HC_BIRC2_3_7; RING finger, HC subclass, found in apoptosis protein c-IAP1, c-IAP2, livin, and similar proteins
    pfam00653
    Location:168 → 232
    BIR; Inhibitor of Apoptosis domain
Nucleotide Protein
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