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MECP2 methyl-CpG binding protein 2 [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100029536, updated on 6-Jun-2024

Summary

Gene symbol
MECP2
Gene description
methyl-CpG binding protein 2
See related
EnsemblRapid:ENSMODG00000065885
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
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Genomic context

Location:
chromosome: X
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) X NC_077235.1 (73769100..73850960, complement)
103 previous assembly MonDom5 (GCF_000002295.2) X NC_008809.1 (14537773..14592621, complement)

Chromosome X - NC_077235.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 187 Neighboring gene interleukin 1 receptor associated kinase 1 Neighboring gene opsin 1 (cone pigments), long-wave-sensitive Neighboring gene testis expressed 28

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables double-stranded methylated DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables methyl-CpG binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of heterochromatin IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
methyl-CpG-binding protein 2
Names
methyl CpG binding protein 2 (Rett syndrome) X-linked

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077235.1 Reference mMonDom1.pri

    Range
    73769100..73850960 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_056809454.1XP_056665432.1  methyl-CpG-binding protein 2 isoform X2

    UniProtKB/TrEMBL
    F6TJ75
    Related
    ENSMODP00000066765.1, ENSMODT00000095575.1
  2. XM_016426627.2XP_016282113.2  methyl-CpG-binding protein 2 isoform X1

    UniProtKB/TrEMBL
    F6TJ54
    Related
    ENSMODP00000077579.1, ENSMODT00000116851.1