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MARCHF8 membrane associated ring-CH-type finger 8 [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100027542, updated on 8-May-2024

Summary

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Gene symbol
MARCHF8
Gene description
membrane associated ring-CH-type finger 8
See related
EnsemblRapid:ENSMODG00000010754
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Also known as
MARCH8
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 1 NC_077227.1 (41191876..41330034)
103 previous assembly MonDom5 (GCF_000002295.2) 1 NC_008801.1 (14588540..14742045)

Chromosome 1 - NC_077227.1Genomic Context describing neighboring genes Neighboring gene WASH complex subunit 2C Neighboring gene uncharacterized LOC130454292 Neighboring gene zinc finger AN1-type containing 4 Neighboring gene uncharacterized LOC130454295 Neighboring gene arachidonate 5-lipoxygenase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MHC protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in antigen processing and presentation of peptide antigen via MHC class II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in late endosome membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase MARCHF8
Names
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077227.1 Reference mMonDom1.pri

    Range
    41191876..41330034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007478073.3 → XP_007478135.1  E3 ubiquitin-protein ligase MARCHF8 isoform X1

    See identical proteins and their annotated locations for XP_007478135.1

    UniProtKB/TrEMBL
    F7A1F5
    Related
    ENSMODP00000065330.1, ENSMODT00000117121.1
    Conserved Domains (1) summary
    smart00744
    Location:361 → 408
    RINGv; The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins

  2. XM_056797564.1 → XP_056653542.1  E3 ubiquitin-protein ligase MARCHF8 isoform X4

    UniProtKB/TrEMBL
    F7FWI4

  3. XM_056797552.1 → XP_056653530.1  E3 ubiquitin-protein ligase MARCHF8 isoform X2

    Related
    ENSMODP00000037712.4, ENSMODT00000039316.5

  4. XM_056797548.1 → XP_056653526.1  E3 ubiquitin-protein ligase MARCHF8 isoform X1

    UniProtKB/TrEMBL
    F7A1F5

  5. XM_056797579.1 → XP_056653557.1  E3 ubiquitin-protein ligase MARCHF8 isoform X4

    UniProtKB/TrEMBL
    F7FWI4

  6. XM_007478072.3 → XP_007478134.1  E3 ubiquitin-protein ligase MARCHF8 isoform X1

    See identical proteins and their annotated locations for XP_007478134.1

    UniProtKB/TrEMBL
    F7A1F5
    Related
    ENSMODP00000066473.1, ENSMODT00000092991.1
    Conserved Domains (1) summary
    smart00744
    Location:361 → 408
    RINGv; The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins

  7. XM_001377772.5 → XP_001377809.2  E3 ubiquitin-protein ligase MARCHF8 isoform X4

    UniProtKB/TrEMBL
    F7FWI4
    Related
    ENSMODP00000013476.2, ENSMODT00000013722.5
    Conserved Domains (1) summary
    smart00744
    Location:76 → 124
    RINGv; The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins

  8. XM_056797555.1 → XP_056653533.1  E3 ubiquitin-protein ligase MARCHF8 isoform X3

Nucleotide Protein
Heading Accession and Version

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