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    Oacyl O-acyltransferase like [ Mus musculus (house mouse) ]

    Gene ID: 319888, updated on 28-Apr-2024

    Summary

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    Official Symbol
    Oacylprovided by MGI
    Official Full Name
    O-acyltransferase likeprovided by MGI
    Primary source
    MGI:MGI:2442915
    See related
    Ensembl:ENSMUSG00000046610 AllianceGenome:MGI:2442915
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Acyl3; 5330437I02Rik
    Summary
    Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human OACYLP (O-acyltransferase like, pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    all
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    Genomic context

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    Location:
    18 E1; 18 38.98 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (65830441..65884695)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (65697370..65751624)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118568360 Neighboring gene STARR-seq mESC enhancer starr_44834 Neighboring gene STARR-seq mESC enhancer starr_44835 Neighboring gene STARR-seq mESC enhancer starr_44838 Neighboring gene zinc finger protein 532 Neighboring gene zinc finger protein 592 pseudogene Neighboring gene predicted gene, 54022 Neighboring gene STARR-positive B cell enhancer ABC_E4252 Neighboring gene STARR-positive B cell enhancer ABC_E618 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:65960619-65960728 Neighboring gene STARR-positive B cell enhancer ABC_E1517 Neighboring gene STARR-positive B cell enhancer ABC_E9984 Neighboring gene STARR-positive B cell enhancer ABC_E1961 Neighboring gene SEC11 homolog C, signal peptidase complex subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Comparative genomics search for losses of long-established genes on the human lineage. Zhu J, et al. PLoS Comput Biol, 2007 Dec. PMID 18085818, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    O-acyltransferase like protein
    Names
    acyltransferase 3
    protein oacyl

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177028.3 → NP_796002.1  O-acyltransferase like protein precursor

      See identical proteins and their annotated locations for NP_796002.1

      Status: PROVISIONAL

      Source sequence(s)
      AC124578
      Consensus CDS
      CCDS29308.1
      UniProtKB/Swiss-Prot
      B9EJ12, E9Q6M1, Q8BMK8, Q8BML2
      Related
      ENSMUSP00000110749.2, ENSMUST00000115097.8
      Conserved Domains (3) summary
      smart00703
      Location:44 → 122
      NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
      COG1835
      Location:276 → 678
      OafA; Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains [Cell wall/membrane/envelope biogenesis]
      pfam01757
      Location:276 → 664
      Acyl_transf_3; Acyltransferase family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      65830441..65884695
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161171.1 → XP_036017064.1  O-acyltransferase like protein isoform X2

      Conserved Domains (2) summary
      smart00703
      Location:44 → 122
      NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
      pfam01757
      Location:308 → 487
      Acyl_transf_3; Acyltransferase family

    2. XM_036161173.1 → XP_036017066.1  O-acyltransferase like protein isoform X4

      Conserved Domains (2) summary
      smart00703
      Location:44 → 122
      NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
      pfam01757
      Location:308 → 427
      Acyl_transf_3; Acyltransferase family

    3. XM_036161174.1 → XP_036017067.1  O-acyltransferase like protein isoform X4

      Conserved Domains (2) summary
      smart00703
      Location:44 → 122
      NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
      pfam01757
      Location:308 → 427
      Acyl_transf_3; Acyltransferase family

    4. XM_036161175.1 → XP_036017068.1  O-acyltransferase like protein isoform X5

      Conserved Domains (2) summary
      smart00703
      Location:44 → 122
      NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
      pfam01757
      Location:308 → 486
      Acyl_transf_3; Acyltransferase family

    5. XM_036161170.1 → XP_036017063.1  O-acyltransferase like protein isoform X1

      Conserved Domains (2) summary
      smart00703
      Location:44 → 122
      NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
      COG1835
      Location:308 → 710
      OafA; Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains [Cell wall/membrane/envelope biogenesis]

    6. XM_036161172.1 → XP_036017065.1  O-acyltransferase like protein isoform X3

      Conserved Domains (1) summary
      COG1835
      Location:118 → 520
      OafA; Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains [Cell wall/membrane/envelope biogenesis]

    RNA

    1. XR_004939865.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BML2.1 GenPept UniProtKB/Swiss-Prot:Q8BML2

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