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    CG5112 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43083, updated on 10-May-2024

    Summary

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    Official Symbol
    CG5112provided by FlyBase
    Primary source
    FLYBASE:FBgn0039341
    Locus tag
    Dmel_CG5112
    See related
    AllianceGenome:FB:FBgn0039341
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5112
    Summary
    Predicted to enable acylglycerol lipase activity and fatty acid amide hydrolase activity. Predicted to be involved in fatty acid catabolic process. Is expressed in adult head; adult heart; and organism. Orthologous to human FAAH2 (fatty acid amide hydrolase 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG5112 in Genome Data Viewer
    Location:
    96E2-96E2; 3-88 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25491460..25493262)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21317182..21318984)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Glyceronephosphate O-acyltransferase Neighboring gene antisense RNA:CR44179 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44948

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genetic screen in Drosophila for regulators of human prostate cancer progression. Ito S, et al. Biochem Biophys Res Commun, 2014 Sep 5. PMID 25117438
    2. Protein correlation profiles identify lipid droplet proteins with high confidence. Krahmer N, et al. Mol Cell Proteomics, 2013 May. PMID 23319140, Free PMC Article
    3. The lipid-droplet proteome reveals that droplets are a protein-storage depot. Cermelli S, et al. Curr Biol, 2006 Sep 19. PMID 16979555
    4. SUMO-Enriched Proteome for Drosophila Innate Immune Response. Handu M, et al. G3 (Bethesda), 2015 Aug 18. PMID 26290570, Free PMC Article
    5. Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasis. Lin WH, et al. Dis Model Mech, 2017 Feb 1. PMID 28067623, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acylglycerol lipase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables fatty acid amide hydrolase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5112-PA
    NP_651400.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25491460..25493262
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143143.3 → NP_651400.1  uncharacterized protein Dmel_CG5112 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651400.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBQ5
      Related
      FBpp0084252
      Conserved Domains (2) summary
      PRK07488
      Location:52 → 513
      PRK07488; indole acetimide hydrolase; Validated
      cl18951
      Location:69 → 502
      Amidase; Amidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VBQ5 Q9VBQ5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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