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    CG12782 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37685, updated on 10-May-2024

    Summary

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    Official Symbol
    CG12782provided by FlyBase
    Primary source
    FLYBASE:FBgn0034838
    Locus tag
    Dmel_CG12782
    See related
    AllianceGenome:FB:FBgn0034838
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12782
    Summary
    Predicted to enable RNA binding activity and ubiquitin binding activity. Predicted to be involved in RNA export from nucleus and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to be part of nuclear pore. Orthologous to human RAE1 (ribonucleic acid export 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG12782 in Genome Data Viewer
    Location:
    59D4-59D4; 2-102 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23264269..23265543, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19151792..19153066, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L22-like Neighboring gene yippee interacting protein 3 Neighboring gene uncharacterized protein Neighboring gene orientation disruptor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila rae1 is required for male meiosis and spermatogenesis. Volpi S, et al. J Cell Sci, 2013 Aug 15. PMID 23788425
    2. Gene expression profiling of brakeless mutant Drosophila embryos. Crona F, et al. Data Brief, 2015 Dec. PMID 26509186, Free PMC Article
    3. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897
    4. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12782-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23264269..23265543 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137928.3 → NP_611772.2  uncharacterized protein Dmel_CG12782 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611772.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4A6, Q9W1T0
      Related
      FBpp0071957
      Conserved Domains (3) summary
      COG2319
      Location:19 → 303
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:26 → 64
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:25 → 303
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T4A6 Q8T4A6
    Q9W1T0 Q9W1T0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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