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    Vav Vav guanine nucleotide exchange factor [ Polistes canadensis ]

    Gene ID: 106787763, updated on 16-May-2024

    Summary

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    Gene symbol
    Vav
    Gene description
    Vav guanine nucleotide exchange factor
    See related
    EnsemblRapid:LOC106787763
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Polistes canadensis
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Vespoidea; Vespidae; Polistinae; Polistini; Polistes
    Orthologs
    fruit fly all
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    Genomic context

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    See Vav in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    100 current ASM131383v1 (GCF_001313835.1) Unplaced Scaffold NW_014569661.1 (293477..299492)

    NW_014569661.1Genomic Context describing neighboring genes Neighboring gene leukocyte elastase inhibitor-like Neighboring gene glutaminyl-peptide cyclotransferase-like Neighboring gene plancitoxin-1 Neighboring gene uncharacterized LOC106787776 Neighboring gene transfer RNA valine (anticodon AAC)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_014569661.1 Unplaced Scaffold Reference ASM131383v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein vav

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Polistes canadensis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM131383v1

    Genomic

    1. NW_014569661.1 Reference ASM131383v1

      Range
      293477..299492
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014750405.1 → XP_014605891.1  protein vav isoform X3

      Related
      XP_014605891.1, XM_014750405.1
      Conserved Domains (7) summary
      cd01223
      Location:406 → 532
      PH_Vav; Vav pleckstrin homology (PH) domain
      pfam00130
      Location:540 → 581
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
      pfam00169
      Location:424 → 527
      PH; PH domain
      pfam00307
      Location:14 → 125
      CH; Calponin homology (CH) domain
      pfam00621
      Location:216 → 389
      RhoGEF; RhoGEF domain
      cl15255
      Location:607 → 718
      SH2; Src homology 2 (SH2) domain
      cl17036
      Location:725 → 776
      SH3; Src Homology 3 domain superfamily

    2. XM_014750406.1 → XP_014605892.1  protein vav isoform X4

      Related
      XP_014605892.1, XM_014750406.1
      Conserved Domains (7) summary
      cd01223
      Location:405 → 531
      PH_Vav; Vav pleckstrin homology (PH) domain
      pfam00130
      Location:539 → 580
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
      pfam00169
      Location:423 → 526
      PH; PH domain
      pfam00307
      Location:14 → 125
      CH; Calponin homology (CH) domain
      pfam00621
      Location:215 → 388
      RhoGEF; RhoGEF domain
      cl15255
      Location:606 → 717
      SH2; Src homology 2 (SH2) domain
      cl17036
      Location:724 → 775
      SH3; Src Homology 3 domain superfamily

    3. XM_014750403.1 → XP_014605889.1  protein vav isoform X1

      Related
      XP_014605889.1, XM_014750403.1
      Conserved Domains (7) summary
      cd01223
      Location:427 → 553
      PH_Vav; Vav pleckstrin homology (PH) domain
      pfam00130
      Location:561 → 602
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
      pfam00169
      Location:445 → 548
      PH; PH domain
      pfam00307
      Location:14 → 125
      CH; Calponin homology (CH) domain
      pfam00621
      Location:237 → 410
      RhoGEF; RhoGEF domain
      cl15255
      Location:628 → 739
      SH2; Src homology 2 (SH2) domain
      cl17036
      Location:746 → 797
      SH3; Src Homology 3 domain superfamily

    4. XM_014750404.1 → XP_014605890.1  protein vav isoform X2

      Related
      XP_014605890.1, XM_014750404.1
      Conserved Domains (7) summary
      cd01223
      Location:426 → 552
      PH_Vav; Vav pleckstrin homology (PH) domain
      pfam00130
      Location:560 → 601
      C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
      pfam00169
      Location:444 → 547
      PH; PH domain
      pfam00307
      Location:14 → 125
      CH; Calponin homology (CH) domain
      pfam00621
      Location:236 → 409
      RhoGEF; RhoGEF domain
      cl15255
      Location:627 → 738
      SH2; Src homology 2 (SH2) domain
      cl17036
      Location:745 → 796
      SH3; Src Homology 3 domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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