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    ATP7 F1F0 ATP synthase subunit d [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853853, updated on 11-Apr-2024

    Summary

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    Gene symbol
    ATP7
    Gene description
    F1F0 ATP synthase subunit d
    Primary source
    SGD:S000001499
    Locus tag
    YKL016C
    See related
    AllianceGenome:SGD:S000001499
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Contributes to proton-transporting ATP synthase activity, rotational mechanism. Involved in ATP synthesis coupled proton transport. Located in mitochondrion. Part of mitochondrial proton-transporting ATP synthase, stator stalk. Orthologous to human ATP5PD (ATP synthase peripheral stalk subunit d). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (407465..407989, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene WD-repeat containing protein SWD2 Neighboring gene ATP-dependent 5'-3' DNA helicase HCS1 Neighboring gene Put3p Neighboring gene Urb1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ATP synthase of yeast mitochondria. Characterization of subunit d and sequence analysis of the structural gene ATP7. Norais N, et al. J Biol Chem, 1991 Sep 5. PMID 1832157
    2. Over-expression of the yeast ATP synthase subunit D in Escherichia coli: use of polyclonal antibodies directed against recombinant subunit D. Norais N, et al. Biochem Biophys Res Commun, 1994 Apr 29. PMID 8179622
    3. The second stalk of the yeast ATP synthase complex: identification of subunits showing cross-links with known positions of subunit 4 (subunit b). Soubannier V, et al. Biochemistry, 1999 Nov 9. PMID 10555984
    4. Single copies of subunits d, oligomycin-sensitivity conferring protein, and b are present in the Saccharomyces cerevisiae mitochondrial ATP synthase. Bateson M, et al. J Biol Chem, 1999 Mar 12. PMID 10066811
    5. Topological and functional study of subunit h of the F1Fo ATP synthase complex in yeast Saccharomyces cerevisiae. Fronzes R, et al. Biochemistry, 2003 Oct 21. PMID 14556635

    See all (79) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables proton transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in ATP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton motive force-driven ATP synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proton motive force-driven ATP synthesis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in proton motive force-driven ATP synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton motive force-driven ATP synthesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial proton-transporting ATP synthase, stator stalk IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial proton-transporting ATP synthase, stator stalk IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mitochondrial proton-transporting ATP synthase, stator stalk IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of proton-transporting ATP synthase complex, coupling factor F(o) IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    F1F0 ATP synthase subunit d
    NP_012909.3
    • Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      407465..407989 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179582.3 → NP_012909.3  TPA: F1F0 ATP synthase subunit d [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012909.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXS0, P30902
      UniProtKB/TrEMBL
      A0A8H4FAB9, B3LR69, B5VMD9, G2WI15, N1P7Y9
      Conserved Domains (1) summary
      pfam05873
      Location:5 → 145
      Mt_ATP-synt_D; ATP synthase D chain, mitochondrial (ATP5H)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P30902.2

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