|
Status |
Public on Jul 01, 2016 |
Title |
17-DMAG treatment in primary CLL B cells |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
|
Summary |
We used microarrays to analyze gene expression following treatment of leukemic B cells with the Hsp90 inhibitor 17-DMAG. Gene expression profiling reveals the role of SOCS3 in cytokine signaling in CLL
|
|
|
Overall design |
Primary cells from CLL patients were isolated and treated in vitro with 17-DMAG. Cells were collected for viability, gene expression analysis and cell signaling and migration assays.
|
|
|
Contributor(s) |
Hertlein E |
Citation(s) |
27107422 |
Submission date |
Jan 05, 2016 |
Last update date |
Mar 25, 2019 |
Contact name |
Lianbo Yu |
Organization name |
The Ohio State University
|
Department |
Center for Biostatistics
|
Lab |
320 Lincoln Tower
|
Street address |
1800 Cannon Drive
|
City |
Columbus |
State/province |
OH |
ZIP/Postal code |
43210 |
Country |
USA |
|
|
Platforms (1) |
GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
Samples (5)
|
|
Relations |
BioProject |
PRJNA307698 |