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Series GSE68665 Query DataSets for GSE68665
Status Public on May 09, 2015
Title Influence of Erythropoietin on Microvesicles Derived from Mesenchymal Ste cells(MSC) protecting renal function of Chronic Kidney Disease
Organism Mus musculus
Experiment type Non-coding RNA profiling by array
Summary miRNA profiles of the MSC-MVs and EPO-MVs were analyzed with a quantitative PCR (qPCR)-based array of the whole mice genome. Further analysis revealed differences in the miRNAs of 212 EPO-MVs (fold change ≥ 1.5 compared to the MSC-MVs), which constituted approximately 22.64% of all of the evaluated mouse miRNAs. Of all of the differences, 70.28% of the changes in the EPO-MV group involved upregulation
Overall design To study the differential miRNA expression in MV and EPO-MV which might contributed to the better treatment in chronic kidney disease, we performed miRNA expression profiling of the culture supernatant of MSC with or without EPO incubation using the miRCURY LNA Array (v.18.0) (Exiqon, Vedbaek, Denmark).
Contributor(s) Wang Y, Zhao W
Citation(s) 25998259
Submission date May 07, 2015
Last update date Aug 13, 2015
Contact name Yan Wang
Phone 18262636355
Organization name the First Affiliated Hospital of Nanjing Medical University
Street address 300 Guangzhou Road
City Nanjing
ZIP/Postal code 210029
Country China
Platforms (1)
GPL20167 Exiqon miRCURY LNA microRNA Array, 7th generation REV - hsa, mmu & rno (miRBase v18.0)
Samples (2)
GSM1678732 Microvesicles derived from erythropoietin co-cultured MSC
GSM1678733 Microvesicles derived from normal cultured MSC
BioProject PRJNA283410

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE68665_RAW.tar 1.9 Mb (http)(custom) TAR (of GPR)
Processed data included within Sample table

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