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Series GSE60482 Query DataSets for GSE60482
Status Public on Feb 18, 2015
Title Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells
Organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary T Cell stretch-enhancers are vulnerable to Jak inhibitor tofacitinib
Overall design Treatment of T cells with the Janus kinase (JAK) inhibitor, tofacitinib, disproportionately altered the expression of RA risk genes with stretech-enhancer (SE) structures.
Contributor(s) Vahedi G, Furumoto Y, Jiang K, Kanno Y, Roychoudhuri R, Restifo NP, Collins F, Sartorelli V, O'Shea JJ
Citation(s) 25686607
Submission date Aug 18, 2014
Last update date May 15, 2019
Contact name Golnaz Vahedi
Organization name National Institutes of Health
Department NIAMS
Lab Lymphocyte Cell Biology Section
Street address 9000 Rockville Pike Bldg 10 Rm 13C101A
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
Platforms (3)
GPL9250 Illumina Genome Analyzer II (Mus musculus)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (21)
GSM1480824 ChIP p300 Th17
GSM1480825 ChIP CTCF Th1
GSM1480826 RNA Th0_no_tofa
BioProject PRJNA258386
SRA SRP045570

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE60482_RAW.tar 3.7 Gb (http)(custom) TAR (of BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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