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Series GSE47987 Query DataSets for GSE47987
Status Public on Jun 02, 2014
Title FoxA1 inhibits androgen receptor expression and suppresses prostate cancer metastasis [DU145, ChIP-seq]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary FoxA1 has been shown critical for prostate development and prostate-specific gene expression regulation. In addition to its well-established role as an AR pioneering factor,several studies have recently revealed significant AR binding events in prostate cancer cells with FoxA1 knockdown. Furthermore, the role of FoxA1 itself in prostate cancer has not been carefully examined. Thus, it is important to understand the role of FoxA1 in prostate cancer and how it interacts with AR signaling.
Overall design ChIP-Seq examination of AR and FoxA1 binding sites, FAIRE-seq detection of open chromatin genomic regions in DU145 AR +/- FOXA1 cells
Contributor(s) Jin H, Yu J
Citation(s) 24875621
Submission date Jun 15, 2013
Last update date May 15, 2019
Contact name Hong-Jian Jin
Phone 3125033041
Organization name Northwestern University
Department Medicine
Street address 303 E Superior St
City Chicago
State/province IL - Illinois
ZIP/Postal code 60611
Country USA
Platforms (2)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (18)
GSM1164140 Input_DU145 Empty Vector
GSM1164141 AR_ChIP-seq_DU145 AR
GSM1164142 AR_ChIP-seq_DU145 AR + FoxA1
This SubSeries is part of SuperSeries:
GSE55007 Cooperativity and Equilibrium with FOXA1 Define Androgen Receptor Transcriptional Program
BioProject PRJNA208545
SRA SRP026074

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE47987_RAW.tar 18.0 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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