 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Mar 18, 2024 |
| Title |
Effect of estrogen on transcriptomic profile in iWAT of old aged mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Beige adipocyes are compromised with aging even upon cold exposure. Besides, estrogen levels, which have metabolic benefit ,are also decreased with aging. However, the relationship between beige adipocyte and estrogen in aging remains poorly understood. In this study, the potential role of estrogen in iWAT of old aged mice was investigated. To elucidate functional outcomes, we performed RNA-sequencing analysis using vehicle treated group and estrogen treated group upon cold exposure
|
| |
|
| Overall design |
To investigate the role of estrogen function in beige adipocytes in iWAT in old aged mice, we performed gene expression analysis using data obtained from RNA-sequencing. comparative gene expression profiling between vehicle treated group and estrogen treated group.
|
| Web link |
https://www.nature.com/articles/s43587-024-00633-z
|
| |
|
| Contributor(s) |
Park J, Jiang Y |
| Citation(s) |
38858606 |
| Submission date |
Mar 13, 2024 |
| Last update date |
Jun 17, 2024 |
| Contact name |
Jooman Park |
| E-mail(s) |
joomanp@uic.edu
|
| Organization name |
University of Illinois at Chicago
|
| Department |
Dept. of Physiology and Biophysics
|
| Lab |
Jiang Yuwei
|
| Street address |
909 S Wolcott Ave COMRB 1120
|
| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60612 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (6)
|
| GSM8144982 |
iWAT, vehicle treated group , Cold 7days, rep1 |
| GSM8144983 |
iWAT, vehicle treated group , Cold 7days, rep2 |
| GSM8144984 |
iWAT, vehicle treated group , Cold 7days, rep3 |
| GSM8144985 |
iWAT, estrogen treated group , Cold 7days, rep1 |
| GSM8144986 |
iWAT, estrogen treated group , Cold 7days, rep2 |
| GSM8144987 |
iWAT, estrogen treated group , Cold 7days, rep3 |
|
| Relations |
| BioProject |
PRJNA1087265 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE261481_Raw_Count.txt.gz |
2.1 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
|
|
|
|
 |
Less...
More...