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| Status |
Public on May 09, 2023 |
| Title |
Effect of GSK3368715 on GBM patient samples, kept in a novel perfusion device for 8-days |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Glioblastoma patient samples were microdissected into ~20mg pieces and put onto a novel perfusion device, within an hour of resection. Samples were left for 8 days, at a flow rate of 3ul/min, with a media change at day 4. Treatment was with 1uM GSK3368715. Please refer to Barry et al. Lab-on-chip 2023 for details.
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| |
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| Overall design |
Four patient GBM samples were treated with 1 uM GSK3368715, or DMSO control via the media supplying the microfluidics system. Samples were numbered 4 to 7, which correspond to patients D31 to D34. Please refer to Barry et al. Lab-on-chip 2023 for details.
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| Web link |
https://pubs.rsc.org/en/content/articlelanding/2023/LC/D3LC00204G
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| |
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| Contributor(s) |
Beltran-Alvarez P, Barry A |
| Citation(s) |
37191188 |
| |
| Submission date |
Mar 06, 2023 |
| Last update date |
May 17, 2023 |
| Contact name |
Pedro Beltran-Alvarez |
| E-mail(s) |
p.beltran-alvarez@hull.ac.uk
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| Organization name |
University of Hull
|
| Department |
HYMS Centre for Biomedicine
|
| Lab |
Hardy 124
|
| Street address |
University of Hull, Cottingham Road
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| City |
Hull |
| ZIP/Postal code |
HU6 7RX |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA941284 |
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