|
| Status |
Public on Jan 01, 2024 |
| Title |
Dual-active oxadiazoles targeting the Mycobacterium tuberculosis ESX-1 secretion system and boosting ethionamide activity |
| Organism |
Mycobacterium tuberculosis |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To find potential regulatory targets of the anti-virulence compound S3 in Mycobacterium tubercuolsis.
|
| |
|
| Overall design |
We checked for differentially expressed genes in Mycobacterium tuberculosis after 4h exposure to compound S3.
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| |
|
| Contributor(s) |
Gries R, Dal Molin M, Chhen J, van Gumpel E, Sonnenkalb L, Utpatel C, Rybniker J |
| Citation missing |
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| |
| Submission date |
Mar 02, 2023 |
| Last update date |
Jan 01, 2024 |
| Contact name |
Raphael Gries |
| E-mail(s) |
raphael.gries@uk-koeln.de
|
| Organization name |
University Hospital Cologne
|
| Street address |
Robert-Koch-Straße 21
|
| City |
Cologne |
| ZIP/Postal code |
50931 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL27507 |
Illumina NovaSeq 6000 (Mycobacterium tuberculosis) |
|
| Samples (4)
|
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| Relations |
| BioProject |
PRJNA940393 |
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