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| Status |
Public on Sep 04, 2023 |
| Title |
Primate-specific ZNF808 is essential for pancreatic development in humans [ChIP-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Functional investigation of the role primate-specific gene ZNF808 over pancreas differentiation. Loss of function of ZNF808 is a cause of pancreatic agenesis, which is a failure of pancreas development.
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| Overall design |
ChIP-seq for H3K27me3 and H3K27ac over timecourse of pancreatic differentiation in WT and ZNF808 KO conditions.
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| Contributor(s) |
Owens N, Imbeault M, Kvist J, Montaser H, Otonkoski T |
| Citation(s) |
37973953 |
| Submission date |
May 31, 2022 |
| Last update date |
Dec 14, 2023 |
| Contact name |
Nick Owens |
| Organization name |
University of Exeter Medical School
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| Street address |
Barrack Road
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| City |
Exeter |
| State/province |
Exeter |
| ZIP/Postal code |
EX2 5DW |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (30)
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| GSM6205955 |
H1, ZNF808KO, S1, H3K9me3 |
| GSM6205956 |
H1, S2, H3K9me3 |
| GSM6205957 |
H1, ZNF808KO, S2, H3K9me3 |
| GSM6205958 |
H1, S3, H3K9me3 |
| GSM6205959 |
H1, ZNF808KO, S3, H3K9me3 |
| GSM6205960 |
H1, S4, H3K9me3 |
| GSM6205961 |
H1, ZNF808KO, S4, H3K9me3 |
| GSM6205968 |
H1, S0, H3K27ac |
| GSM6205969 |
H1, ZNF808KO, S0, H3K27ac |
| GSM6205970 |
H1, S1, H3K27ac |
| GSM6205971 |
H1, ZNF808KO, S1, H3K27ac |
| GSM6205972 |
H1, S2, H3K27ac |
| GSM6205973 |
H1, ZNF808KO, S2, H3K27ac |
| GSM6205974 |
H1, S3, H3K27ac |
| GSM6205975 |
H1, ZNF808KO, S3, H3K27ac |
| GSM6205976 |
H1, S4, H3K27ac |
| GSM6205977 |
H1, ZNF808KO, S4, H3K27ac |
| GSM6205984 |
H1, S0, input |
| GSM6205985 |
H1, ZNF808KO, S0, input |
| GSM6205986 |
H1, S1, input |
| GSM6205987 |
H1, ZNF808KO, S1, input |
| GSM6205988 |
H1, S2, input |
| GSM6205989 |
H1, ZNF808KO, S2, input |
| GSM6205990 |
H1, S3, input |
| GSM6205991 |
H1, ZNF808KO, S3, input |
| GSM6205992 |
H1, S4, input |
| GSM6205993 |
H1, ZNF808KO, S4, input |
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| This SubSeries is part of SuperSeries: |
| GSE205164 |
Primate-specific ZNF808 is essential for pancreatic development in humans |
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| Relations |
| BioProject |
PRJNA844007 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE205152_RAW.tar |
24.3 Mb |
(http)(custom) |
TAR (of BROADPEAK) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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