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| Status |
Public on Dec 06, 2023 |
| Title |
Single cell-seq identify discoid lateral meniscus |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Discoid lateral meniscus (DLM) is more prone to injury than a normally shaped meniscus. Our previous study successfully identified the different cell types and their corresponding marker genes in meniscus tissues, but there was no study comparing the gene expression and cell heterogenicity of discoid meniscus with normal meniscus.
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| Overall design |
scRNA-seq was used to identify cell subsets and their gene signatures in DLM and osteoarthritis lateral meniscus (OAM) cells to determine their differentiation relationships and identify specific cell types. Pseudotime analysis and immunohistochemical staining were used to investigate temporal and spatial distribution of DLM specific clusters
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| Contributor(s) |
Sun H, Ma R |
| Citation missing |
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| Submission date |
Dec 07, 2020 |
| Last update date |
Dec 06, 2023 |
| Contact name |
Hao Sun |
| E-mail(s) |
sunhaojnsysu@foxmail.com
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| Phone |
15017541945
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| Organization name |
First Affiliated Hospital of Sun Yat-sen University,
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| Department |
Joint surgery
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| Street address |
Zhongshan 2nd Road
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| City |
Guangzhou |
| State/province |
Guangdong |
| ZIP/Postal code |
510220 |
| Country |
China |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA682995 |
| SRA |
SRP296773 |
