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Status |
Public on Oct 22, 2020 |
Title |
Transcriptome analysis reveals downregulation of urocortin expression in the hypothalamo-neurohypophysial system of Spontaneously Hypertensive rats |
Organism |
Rattus norvegicus |
Experiment type |
Expression profiling by array
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Summary |
Tissue extracted from the Supraoptic nucleus (SON), paraventricular nucleus (PVN) to determine gene expression differences as a consequence of hypertension within these structures
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Overall design |
SHR and WKY animals at 12-weeks were sacrificed and the PVN and SON were fine dissected.
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Web link |
https://doi.org/10.3389/fphys.2020.599507
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Contributor(s) |
Murphy D, Hindmarch C, Martin A, Mecawi AS, Antunes VR, Antunes-Rodrigues J, Paton JF, Paterson A, Greenwood M, Šarenac O, Savić B, Žigon NJ |
Citation(s) |
33815127 |
Submission date |
Oct 21, 2020 |
Last update date |
Apr 07, 2021 |
Contact name |
DAVID MURPHY |
Organization name |
University of Bristol
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Department |
Medicine and Dentistry
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Lab |
Laboratories for Integrative Neuroscience and Endocrinolgy
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Street address |
Whitson Street
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City |
Bristol |
State/province |
AVON |
ZIP/Postal code |
BS1 3NY |
Country |
United Kingdom |
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Platforms (1) |
GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
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Samples (19)
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Relations |
BioProject |
PRJNA670334 |