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Series GSE102796 Query DataSets for GSE102796
Status Public on Aug 18, 2017
Title Mutant p53 Shapes the Enhancer Landscape of Cancer Cells in Response to Chronic Immune Signaling
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
Summary We establish a mechanism by which chronic TNF-a signaling orchestrates a functional interplay between mutant p53 and NFkB that underlies altered patterns of cancer promoting gene expression.
Overall design examination of various histone mark accumulation; mutp53, NFkB, RNAPII binding; and nascent transcription upon chronic TNF signaling in SW480 colon cancer cells
Contributor(s) Rahnamoun H, Lu H, Duttke SH, Benner C, Glass CK
Citation(s) 28963538, 30076409
Submission date Aug 18, 2017
Last update date Jul 25, 2021
Contact name Shannon M Lauberth
Organization name UCSD
Department Biological Sciences
Lab Lauberth Lab
Street address 9500 Gilman Drive #0322, Bonner Hall 3202
City San Diego
State/province California
ZIP/Postal code 92093
Country USA
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (17)
GSM2746533 0 hr TNF-a GRO-seq
GSM2746534 16 hr TNF-a GRO-seq
GSM2746535 0 hr TNF-a H3K4me1 ChIP-seq
BioProject PRJNA399115
SRA SRP115797

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE102796_GeneExpression.csv.gz 3.4 Mb (ftp)(http) CSV
GSE102796_RAW.tar 1.6 Gb (http)(custom) TAR (of BIGWIG)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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