U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    MIR1244-2 microRNA 1244-2 [ Homo sapiens (human) ]

    Gene ID: 100422885, updated on 10-Oct-2023

    Summary

    Official Symbol
    MIR1244-2provided by HGNC
    Official Full Name
    microRNA 1244-2provided by HGNC
    Primary source
    HGNC:HGNC:38321
    See related
    Ensembl:ENSG00000283498 miRBase:MI0015974; AllianceGenome:HGNC:38321
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
    Annotation information
    Note: MIR1244-2 (GeneID 100422885) was annotated incorrectly on NCBI's Annotation Release 105. Its correct location is chr12: 12264886-12264970 (+). [17 Jun 2014]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    5q23.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (118974586..118974670)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (119487639..119487723)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (118310281..118310365)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901052 Neighboring gene RNA, U7 small nuclear 34 pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr5:118134858-118136057 Neighboring gene NANOG hESC enhancer GRCh37_chr5:118158043-118158570 Neighboring gene DTW domain containing 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:118282316-118282836 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:118282837-118283356 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:118285193-118285694 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:118286400-118287290 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16260 Neighboring gene prothymosin alpha pseudogene 2 Neighboring gene N-acetylneuraminic acid phosphatase pseudogene Neighboring gene DMXL1 divergent transcript Neighboring gene RNA, U6 small nuclear 373, pseudogene Neighboring gene CATSPER2 pseudogene 2

    Genomic regions, transcripts, and products

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_036262.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AC008629
      Related
      ENST00000636449.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      118974586..118974670
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      119487639..119487723
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)