| A genome-wide association study implicates the pleiotropic effect of NMUR2 on asthma and COPD. | A genome-wide association study implicates the pleiotropic effect of NMUR2 on asthma and COPD.
Do AR, An J, Jo J, Kim WJ, Kang HY, Lee S, Yoon D, Cho YS, Adcock IM, Chung KF, Won S, Kim TB., Free PMC Article | 03/3/2023 |
| Activation by NMU2 is longer lasting if NmS is the ligand. | Ligand-Specific Signaling Profiles and Resensitization Mechanisms of the Neuromedin U2 Receptor.
Alhosaini K, Bahattab O, Qassam H, Challiss RAJ, Willars GB. | 02/23/2019 |
| NMU might contribute to progression of NMUR2-positive breast cancer | Oncogenic features of neuromedin U in breast cancer are associated with NMUR2 expression involving crosstalk with members of the WNT signaling pathway.
Garczyk S, Klotz N, Szczepanski S, Denecke B, Antonopoulos W, von Stillfried S, Knüchel R, Rose M, Dahl E., Free PMC Article | 03/31/2018 |
| polymorphisms in the gene may be useful in identifying women at risk for osteoporosis. | Polymorphisms in neuropeptide genes and bone mineral density in Korean postmenopausal women.
Chun EH, Kim H, Suh CS, Kim JH, Kim DY, Kim JG. | 08/20/2016 |
| Study identified a novel NMUR2 splice variant lacking the third exon and able to form heteromeric complexes with NMUR1 and NMUR2 without Neuromedin U (NMU). Its expression can block NMU signaling suppressing then ovarian cancer cells proliferation. | Identifying a Neuromedin U Receptor 2 Splice Variant and Determining Its Roles in the Regulation of Signaling and Tumorigenesis In Vitro.
Lin TY, Huang WL, Lee WY, Luo CW., Free PMC Article | 05/28/2016 |
| A cell-based reporter gene assay has been developed and used for the screening of the human NMU2R agonist. | Chemical genetic analysis reveals the effects of NMU2R on the expression of peptide hormones.
Fang L, Zhang M, Li C, Dong S, Hu Y. | 01/21/2010 |