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    ccc2 Cu(2+) transporting ATPase Ccc2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540525, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ccc2
    Official Full Name
    Cu(2+) transporting ATPase Ccc2
    Primary source
    PomBase:SPBC29A3.01
    Locus tag
    SPOM_SPBC29A3.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ccc2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2037393..2040717)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MPP complex beta subunit Qcr1 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene TIM22 inner membrane protein import complex and succinate dehydrogenase (SDH) anchor subunit Tim18 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase His7 Neighboring gene ubiquitin-protein ligase E3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Copper distributed by Atx1 is available to copper amine oxidase 1 in Schizosaccharomyces pombe. Peter C, et al. Eukaryot Cell, 2008 Oct. PMID 18723604, Free PMC Article
    2. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article
    3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables P-type divalent copper transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables P-type monovalent copper transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables copper ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in copper ion export ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in copper ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular copper ion homeostasis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus HDA PubMed 
    is_active_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Cu(2+) transporting ATPase Ccc2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2037393..2040717
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021733.3 → NP_595829.1  Cu(2+) transporting ATPase Ccc2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595829.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O59666
      Conserved Domains (4) summary
      COG2217
      Location:1 → 837
      ZntA; Cation transport ATPase [Inorganic ion transport and metabolism]
      COG4087
      Location:670 → 791
      COG4087; Soluble P-type ATPase [General function prediction only]
      cd00371
      Location:5 → 68
      HMA; Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain ...
      pfam00122
      Location:285 → 518
      E1-E2_ATPase; E1-E2 ATPase
    Nucleotide Protein
    Heading Accession and Version

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