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    CG33144 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36131, updated on 10-May-2024

    Summary

    Official Symbol
    CG33144provided by FlyBase
    Primary source
    FLYBASE:FBgn0053144
    Locus tag
    Dmel_CG33144
    See related
    AllianceGenome:FB:FBgn0053144
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AAF58756.2; CG12339; CG7621; Dmel\CG33144; lincRNA.281
    Summary
    Predicted to enable ubiquitin conjugating enzyme binding activity; ubiquitin protein ligase activity; and zinc ion binding activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including embryonic proventriculus; embryonic/larval fat body; embryonic/larval muscle system; extended germ band embryo; and visceral muscle primordium. Orthologous to several human genes including RNF144A (ring finger protein 144A). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See CG33144 in Genome Data Viewer
    Location:
    47B9-47B14; 2-63 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10740054..10798709, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6627559..6686214, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene D-amino acid oxidase 1 Neighboring gene uncharacterized protein Neighboring gene Menage a trois 1 Neighboring gene long non-coding RNA:CR43605 Neighboring gene long non-coding RNA:CR44299 Neighboring gene long non-coding RNA:CR44300 Neighboring gene long non-coding RNA:CR44301 Neighboring gene methuselah-like 13 Neighboring gene windei Neighboring gene uncharacterized protein Neighboring gene Nop10 ribonucleoprotein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ubiquitin-dependent protein catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG33144-PA
    CG33144-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10740054..10798709 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001201975.2NP_001188904.1  uncharacterized protein Dmel_CG33144, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188904.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JR34
      Conserved Domains (2) summary
      smart00647
      Location:850956
      IBR; In Between Ring fingers
      pfam01485
      Location:9761014
      IBR; IBR domain, a half RING-finger domain
    2. NM_176144.2NP_788324.1  uncharacterized protein Dmel_CG33144, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788324.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JR34
      Related
      FBpp0087349
      Conserved Domains (2) summary
      smart00647
      Location:850956
      IBR; In Between Ring fingers
      pfam01485
      Location:9761014
      IBR; IBR domain, a half RING-finger domain