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    CG6610 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38693, updated on 26-Apr-2024

    Summary

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    Official Symbol
    CG6610provided by FlyBase
    Primary source
    FLYBASE:FBgn0035675
    Locus tag
    Dmel_CG6610
    See related
    AllianceGenome:FB:FBgn0035675
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE60135; Dmel\CG6610
    Summary
    Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of Lsm1-7-Pat1 complex; spliceosomal complex; and spliceosomal snRNP complex. Is expressed in organism. Orthologous to human LSM5 (LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    65A5-65A5; 3-16 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6075536..6076258)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6068636..6069358)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene short spindle 6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Accelerated sequence divergence of conserved genomic elements in Drosophila melanogaster. Holloway AK, et al. Genome Res, 2008 Oct. PMID 18583644, Free PMC Article
    2. Pre-messenger RNA processing factors in the Drosophila genome. Mount SM, et al. J Cell Biol, 2000 Jul 24. PMID 10908584, Free PMC Article
    3. The genetic architecture of odor-guided behavior in Drosophila melanogaster. Anholt RR, et al. Behav Genet, 2001 Jan. PMID 11529271
    4. spenito is required for sex determination in Drosophila melanogaster. Yan D, et al. Proc Natl Acad Sci U S A, 2015 Sep 15. PMID 26324914, Free PMC Article
    5. Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. Li H, et al. DNA Res, 2016 Dec. PMID 27559081, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    contributes_to RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Lsm1-7-Pat1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U6 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of spliceosomal complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6610-PA
    CG6610-PB
    CG6610-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6075536..6076258
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139765.4 → NP_648022.1  uncharacterized protein Dmel_CG6610, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648022.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VRT7
      Related
      FBpp0076756
      Conserved Domains (1) summary
      cd01732
      Location:12 → 87
      LSm5; Like-Sm protein 5

    2. NM_001274533.1 → NP_001261462.1  uncharacterized protein Dmel_CG6610, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261462.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VRT7
      Conserved Domains (1) summary
      cd01732
      Location:12 → 87
      LSm5; Like-Sm protein 5

    3. NM_001274532.1 → NP_001261461.1  uncharacterized protein Dmel_CG6610, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261461.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VRT7
      Conserved Domains (1) summary
      cd01732
      Location:12 → 87
      LSm5; Like-Sm protein 5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VRT7 Q9VRT7

    Gene LinkOut

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