POLG2 DNA polymerase gamma 2, accessory subunit [Panthera tigris (tiger)] - Gene

Summary

Gene symbol: POLG2
Gene description: DNA polymerase gamma 2, accessory subunit
See related: Ensembl:ENSPTIG00000009776
Gene type: protein coding
RefSeq status: MODEL
Organism: Panthera tigris
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs: human mouse all
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Genomic context

Location:: chromosome: E1

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
102	current	P.tigris_Pti1_mat1.1 (GCF_018350195.1)	E1	NC_056673.1 (46409306..46450177, complement)

Chromosome E1 - NC_056673.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_056673.1 Chromosome E1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in mitochondrial DNA replication	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: DNA polymerase subunit gamma-2, mitochondrial

Names: polymerase (DNA directed), gamma 2, accessory subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

NC_056673.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Range

46409306..46450177 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_042967211.1 → XP_042823145.1 DNA polymerase subunit gamma-2, mitochondrial isoform X2

Conserved Domains (2) summary

cd02426
Location:354 → 472

Pol_gamma_b_Cterm; C-terminal domain of mitochondrial DNA polymerase gamma B subunit, which is required for processivity. Polymerase gamma replicates and repairs mitochondrial DNA. The c-terminal domain of its B subunit is strikingly similar to the anticodon-binding domain ...

cl00268
Location:69 → 350

class_II_aaRS-like_core; Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches ...
XM_007088287.3 → XP_007088349.1 DNA polymerase subunit gamma-2, mitochondrial isoform X5

Conserved Domains (2) summary

cl00266
Location:324 → 407

HGTP_anticodon; HGTP anticodon binding domain, as found at the C-terminus of histidyl, glycyl, threonyl and prolyl tRNA synthetases, which are classified as a group of class II aminoacyl-tRNA synthetases (aaRS). In aaRSs, the anticodon binding domain is responsible for ...

cl00268
Location:69 → 318

class_II_aaRS-like_core; Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches ...
XM_007088284.3 → XP_007088346.1 DNA polymerase subunit gamma-2, mitochondrial isoform X3

UniProtKB/TrEMBL

A0A8C9JZC3

Related

ENSPTIP00000008404.1

Conserved Domains (2) summary

cl00266
Location:354 → 454

HGTP_anticodon; HGTP anticodon binding domain, as found at the C-terminus of histidyl, glycyl, threonyl and prolyl tRNA synthetases, which are classified as a group of class II aminoacyl-tRNA synthetases (aaRS). In aaRSs, the anticodon binding domain is responsible for ...

cl00268
Location:69 → 350

class_II_aaRS-like_core; Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches ...
XM_007088286.3 → XP_007088348.1 DNA polymerase subunit gamma-2, mitochondrial isoform X4

Conserved Domains (2) summary

cl00266
Location:354 → 433

HGTP_anticodon; HGTP anticodon binding domain, as found at the C-terminus of histidyl, glycyl, threonyl and prolyl tRNA synthetases, which are classified as a group of class II aminoacyl-tRNA synthetases (aaRS). In aaRSs, the anticodon binding domain is responsible for ...

cl00268
Location:69 → 350

class_II_aaRS-like_core; Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches ...
XM_007088283.3 → XP_007088345.1 DNA polymerase subunit gamma-2, mitochondrial isoform X1

UniProtKB/TrEMBL

A0A8C9JLV1

Related

ENSPTIP00000008413.1

Conserved Domains (2) summary

cd02426
Location:354 → 481

Pol_gamma_b_Cterm; C-terminal domain of mitochondrial DNA polymerase gamma B subunit, which is required for processivity. Polymerase gamma replicates and repairs mitochondrial DNA. The c-terminal domain of its B subunit is strikingly similar to the anticodon-binding domain ...

cl00268
Location:69 → 350

class_II_aaRS-like_core; Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches ...