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    CG40191 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3354930, updated on 10-May-2024

    Summary

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    Official Symbol
    CG40191provided by FlyBase
    Primary source
    FLYBASE:FBgn0058191
    Locus tag
    Dmel_CG40191
    See related
    AllianceGenome:FB:FBgn0058191
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD12604; BEST:HL02313; Dmel\CG40191
    Summary
    Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in nucleus. Orthologous to human CNPPD1 (cyclin Pas1/PHO80 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG40191 in Genome Data Viewer
    Location:
    41A1-41A1; 2-55 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (1264140..1267747)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2RHet NW_001848856.1 (390773..394380)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene long non-coding RNA:CR44042 Neighboring gene yeti

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. B.2.16 is a non-lethal modifier of the Dark(82) mosaic eye phenotype in Drosophila melanogaster. Vrailas-Mortimer AD, et al. MicroPubl Biol, 2021 Jan 18. PMID 33474526, Free PMC Article
    2. Adaptation of gene loci to heterochromatin in the course of Drosophila evolution is associated with insulator proteins. Funikov SY, et al. Sci Rep, 2020 Jul 17. PMID 32681087, Free PMC Article
    3. Cytogenetic and molecular characterization of heterochromatin gene models in Drosophila melanogaster. Rossi F, et al. Genetics, 2007 Feb. PMID 17110485, Free PMC Article
    4. Comparative Genomic Analyses Provide New Insights into the Evolutionary Dynamics of Heterochromatin in Drosophila. Caizzi R, et al. PLoS Genet, 2016 Aug. PMID 27513559, Free PMC Article
    5. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cyclin-dependent protein kinase holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG40191-PA
    CG40191-PB
    CG40191-PC
    CG40191-PD
    CG40191-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      1264140..1267747
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001015176.3 → NP_001015176.1  uncharacterized protein Dmel_CG40191, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001015176.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZH9
      Conserved Domains (1) summary
      cl00050
      Location:71 → 155
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...

    2. NM_001015175.5 → NP_001015175.1  uncharacterized protein Dmel_CG40191, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001015175.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZH9
      Conserved Domains (1) summary
      cl00050
      Location:71 → 155
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...

    3. NM_001015174.4 → NP_001015174.1  uncharacterized protein Dmel_CG40191, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001015174.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7PLT1
      Conserved Domains (1) summary
      cl00050
      Location:89 → 173
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...

    4. NM_001110883.3 → NP_001104353.1  uncharacterized protein Dmel_CG40191, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001104353.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZH9
      Conserved Domains (1) summary
      cl00050
      Location:71 → 155
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...

    5. NM_001276226.1 → NP_001263155.1  uncharacterized protein Dmel_CG40191, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001263155.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3DMV3
      Conserved Domains (1) summary
      cl06673
      Location:11 → 52
      Extradiol_Dioxygenase_3A_like; Subunit A of Class III extradiol dioxygenases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    D3DMV3 D3DMV3
    Q7PLT1 Q7PLT1
    Q8MZH9 Q8MZH9

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