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    slc12a2l solute carrier family 12 member 2-like [ Danio rerio (zebrafish) ]

    Gene ID: 100537771, updated on 11-Apr-2024

    Summary

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    Official Symbol
    slc12a2lprovided by ZNC
    Official Full Name
    solute carrier family 12 member 2-likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-210112-1
    See related
    AllianceGenome:ZFIN:ZDB-GENE-210112-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    slc12a2b
    Summary
    Predicted to enable cation:chloride symporter activity. Predicted to act upstream of or within sodium ion transport and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    all
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    Genomic context

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    Location:
    chromosome: 8
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (426846..435853, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003337130.1 (70455..79172)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene protein geranylgeranyltransferase type I, beta subunit Neighboring gene fem-1 homolog c Neighboring gene GRAM domain containing 2B Neighboring gene uncharacterized LOC101884619

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Neuronal activity disrupts myelinated axon integrity in the absence of NKCC1b. Marshall-Phelps KLH, et al. J Cell Biol, 2020 Jul 6. PMID 32364583, Free PMC Article
    2. TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice. Moyon S, et al. Nat Commun, 2021 Jun 7. PMID 34099715, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chloride:monoatomic cation symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables salt transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within myelination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 12 member 2-like
    Names
    solute carrier family 12 member 2b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      426846..435853 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003201740.5 → XP_003201788.4  solute carrier family 12 member 2-like

      UniProtKB/TrEMBL
      A0A8M1RPE8
      Conserved Domains (1) summary
      TIGR00930
      Location:107 → 1091
      2a30; K-Cl cotransporter
    Nucleotide Protein Strain
    Heading Accession and Version

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