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    MKS1 Mks1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855648, updated on 9-Jun-2024

    Summary

    Gene symbol
    MKS1
    Gene description
    Mks1p
    Primary source
    FungiDB:YNL076W
    Locus tag
    YNL076W
    See related
    SGD:S000005020; AllianceGenome:SGD:S000005020; VEuPathDB:YNL076W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    LYS80
    Summary
    Involved in several processes, including mitochondria-nucleus signaling pathway; negative regulation of transcription by RNA polymerase II; and regulation of pseudohyphal growth. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See MKS1 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (483556..485310)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Nis1p Neighboring gene Apj1p Neighboring gene snoRNA-binding rRNA-processing protein IMP4 Neighboring gene Mlf3p

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    Mks1p
    NP_014323.1
    • Pleiotropic negative transcriptional regulator; involved in Ras-CAMP and lysine biosynthetic pathways and nitrogen regulation; involved in retrograde (RTG) mitochondria-to-nucleus signaling

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      483556..485310
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182914.1NP_014323.1  TPA: Mks1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014323.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1A3, P34072, Q02533
      UniProtKB/TrEMBL
      A0A8H4BY21, B3LNT5, C8ZGF4, N1NXZ2
      Conserved Domains (1) summary
      pfam08550
      Location:3764
      DUF1752; Fungal protein of unknown function (DUF1752)