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    LOC412739 roundabout homolog 2 [ Apis mellifera (honey bee) ]

    Gene ID: 412739, updated on 9-Nov-2023

    Summary

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    Gene symbol
    LOC412739
    Gene description
    roundabout homolog 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Apis mellifera
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea; Anthophila; Apidae; Apis
    Also known as
    robo; GB40316
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    Genomic context

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    Location:
    chromosome: LG16
    Exon count:
    11
    Annotation release Status Assembly LG Location
    104 current Amel_HAv3.1 (GCF_003254395.2) LG16 NC_037653.1 (609777..654932, complement)
    103 previous assembly Amel_4.5 (GCF_000002195.4) LG16 NC_007085.3 (191121..237093)

    Linkage Group LG16 - NC_037653.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC113219293 Neighboring gene kanadaptin Neighboring gene uncharacterized LOC550975 Neighboring gene uncharacterized LOC107965672 Neighboring gene G-protein coupled receptor Mth2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Differential expression of endogenous plant cell wall degrading enzyme genes in the stick insect (Phasmatodea) midgut. Shelomi M, et al. BMC Genomics, 2014 Oct 21. PMID 25331961, Free PMC Article
    2. Insights into social insects from the genome of the honeybee Apis mellifera. Honeybee Genome Sequencing Consortium. Nature, 2006 Oct 26. PMID 17073008, Free PMC Article
    3. ProtoBee: hierarchical classification and annotation of the honey bee proteome. Kaplan N, et al. Genome Res, 2006 Nov. PMID 17065614, Free PMC Article
    4. Finding the missing honey bee genes: lessons learned from a genome upgrade. Elsik CG, et al. BMC Genomics, 2014 Jan 30. PMID 24479613, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables axon guidance receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Roundabout signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in axon midline choice point recognition IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    roundabout homolog 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Apis mellifera Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Amel_HAv3.1 Primary Assembly

    Genomic

    1. NC_037653.1 Reference Amel_HAv3.1 Primary Assembly

      Range
      609777..654932 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_396192.7 → XP_396192.5  roundabout homolog 2

      UniProtKB/TrEMBL
      A0A7M7R7Y4, A0A8B9AZN8
      Conserved Domains (4) summary
      cd05725
      Location:238 → 306
      Ig3_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
      cd00063
      Location:516 → 606
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam13927
      Location:410 → 485
      Ig_3; Immunoglobulin domain
      cl11960
      Location:26 → 123
      Ig; Immunoglobulin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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