U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    TMEM185B transmembrane protein 185B [ Homo sapiens (human) ]

    Gene ID: 79134, updated on 5-Mar-2024

    Summary

    Official Symbol
    TMEM185Bprovided by HGNC
    Official Full Name
    transmembrane protein 185Bprovided by HGNC
    Primary source
    HGNC:HGNC:18896
    See related
    Ensembl:ENSG00000226479 AllianceGenome:HGNC:18896
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FAM11B
    Summary
    Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    2q14.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (120217479..120223400, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (120652239..120658160, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (120975055..120980976, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene MT-ND4 pseudogene 26 Neighboring gene MT-ND5 pseudogene 28 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11916 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:120981014-120981174 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:120981269-120981932 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16456 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16457 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16458 Neighboring gene uncharacterized LOC105373583 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:120995479-120996678 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:121000550-121001500 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:121003065-121003640 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:121003641-121004217 Neighboring gene RAS like proto-oncogene B Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11918 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16459 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:121041209-121041722 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16460 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr2:121048087-121048782 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:121070991-121071514 Neighboring gene uncharacterized LOC105373584

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ11654, FLJ20979, FLJ33661

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane protein 185B
    Names
    ee3_2
    family with sequence similarity 11, member B
    putative transmembrane protein 185B
    transmembrane protein 185B (pseudogene)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024121.3NP_077026.2  transmembrane protein 185B

      See identical proteins and their annotated locations for NP_077026.2

      Status: VALIDATED

      Source sequence(s)
      AC012363
      Consensus CDS
      CCDS58722.1
      UniProtKB/Swiss-Prot
      A8K1G5, Q53T33, Q66K44, Q8IZ77, Q9H7F4
      Related
      ENSP00000453399.1, ENST00000426077.3
      Conserved Domains (1) summary
      pfam10269
      Location:31253
      Tmemb_185A; Transmembrane Fragile-X-F protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      120217479..120223400 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      120652239..120658160 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)