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    Cers5 ceramide synthase 5 [ Mus musculus (house mouse) ]

    Gene ID: 71949, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cers5provided by MGI
    Official Full Name
    ceramide synthase 5provided by MGI
    Primary source
    MGI:MGI:1919199
    See related
    Ensembl:ENSMUSG00000023021
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    L; Cer; Trh; Trh4; Lass5; AU045339; AW544927; 2310081H14Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 25.1), CNS E18 (RPKM 20.0) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Cers5 in Genome Data Viewer
    Location:
    15; 15 F1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (99633473..99670396, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (99735592..99772515, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (99566023..99602946, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene 16537 Neighboring gene glycerol-3-phosphate dehydrogenase 1 (soluble) Neighboring gene cytochrome c oxidase assembly protein 14 Neighboring gene LIM domain and actin binding 1 Neighboring gene VISTA enhancer mm17 Neighboring gene predicted gene, 25897

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables N-acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables sphingosine N-acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables sphingosine N-acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables sphingosine N-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ceramide synthase 5
    Names
    LAG1 homolog, ceramide synthase 5
    LAG1 longevity assurance homolog 5
    TRAM homolog 4
    longevity assurance homolog 5
    sphingosine N-acyltransferase CERS5
    translocating chain-associating membrane protein homolog 4
    NP_082291.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028015.2NP_082291.1  ceramide synthase 5

      See identical proteins and their annotated locations for NP_082291.1

      Status: PROVISIONAL

      Source sequence(s)
      BC046797
      Consensus CDS
      CCDS27830.1
      UniProtKB/Swiss-Prot
      Q9D6K9
      Related
      ENSMUSP00000023762.7, ENSMUST00000023762.13
      Conserved Domains (2) summary
      smart00724
      Location:139340
      TLC; TRAM, LAG1 and CLN8 homology domains
      cd00086
      Location:87136
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      99633473..99670396 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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