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    Rpap3 RNA polymerase II associated protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 71919, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rpap3provided by MGI
    Official Full Name
    RNA polymerase II associated protein 3provided by MGI
    Primary source
    MGI:MGI:1277218
    See related
    Ensembl:ENSMUSG00000022466
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D15Ertd682; D15Ertd682e; 2310042P20Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 11.3), CNS E18 (RPKM 8.9) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rpap3 in Genome Data Viewer
    Location:
    15 F1; 15 53.54 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (97572978..97603746, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (97675097..97705822, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (97505536..97536253, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41393 Neighboring gene predicted gene, 41394 Neighboring gene endonuclease, polyU-specific Neighboring gene Rap guanine nucleotide exchange factor (GEF) 3 Neighboring gene predicted gene, 33531

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    part_of R2TP complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    RNA polymerase II-associated protein 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028003.2NP_082279.1  RNA polymerase II-associated protein 3

      See identical proteins and their annotated locations for NP_082279.1

      Status: PROVISIONAL

      Source sequence(s)
      AK009765
      Consensus CDS
      CCDS27782.1
      UniProtKB/Swiss-Prot
      Q9D706
      Related
      ENSMUSP00000023104.6, ENSMUST00000023104.7
      Conserved Domains (5) summary
      smart00028
      Location:134167
      TPR; Tetratricopeptide repeats
      sd00006
      Location:134162
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:203235
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:283348
      TPR_11; TPR repeat
      pfam13877
      Location:540631
      RPAP3_C; Potential Monad-binding region of RPAP3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      97572978..97603746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159597.1XP_036015490.1  RNA polymerase II-associated protein 3 isoform X1

      Conserved Domains (4) summary
      PLN03088
      Location:137257
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      TIGR00990
      Location:112385
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:134162
      TPR; TPR repeat [structural motif]
      pfam13877
      Location:540616
      RPAP3_C; Potential Monad-binding region of RPAP3
    2. XM_011245735.2XP_011244037.1  RNA polymerase II-associated protein 3 isoform X2

      Conserved Domains (3) summary
      PLN03088
      Location:135270
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      sd00006
      Location:124152
      TPR; TPR repeat [structural motif]
      pfam13877
      Location:380467
      RPAP3_C; Potential Monad-binding region of RPAP3
    3. XM_036159598.1XP_036015491.1  RNA polymerase II-associated protein 3 isoform X3

      Conserved Domains (3) summary
      PLN03088
      Location:2105
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      sd00006
      Location:2656
      TPR; TPR repeat [structural motif]
      pfam13877
      Location:215302
      RPAP3_C; Potential Monad-binding region of RPAP3
    4. XM_030248782.2XP_030104642.1  RNA polymerase II-associated protein 3 isoform X3

      Conserved Domains (3) summary
      PLN03088
      Location:2105
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      sd00006
      Location:2656
      TPR; TPR repeat [structural motif]
      pfam13877
      Location:215302
      RPAP3_C; Potential Monad-binding region of RPAP3
    5. XM_030248783.1XP_030104643.1  RNA polymerase II-associated protein 3 isoform X3

      Conserved Domains (3) summary
      PLN03088
      Location:2105
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      sd00006
      Location:2656
      TPR; TPR repeat [structural motif]
      pfam13877
      Location:215302
      RPAP3_C; Potential Monad-binding region of RPAP3
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