Format

Send to:

Choose Destination
    • Showing Current items.

    Klhdc3 kelch domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 71765, updated on 8-Jul-2021

    Summary

    Official Symbol
    Klhdc3provided by MGI
    Official Full Name
    kelch domain containing 3provided by MGI
    Primary source
    MGI:MGI:2651568
    See related
    Ensembl:ENSMUSG00000063576
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P; Peas; 1300011D16Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 250.5), cortex adult (RPKM 57.9) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Klhdc3 in Genome Data Viewer
    Location:
    17 22.9 cM; 17 C
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (46985476..46991856, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (46674550..46680930, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (46811499..46817879, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene cullin 7 Neighboring gene ribosomal RNA processing 36 Neighboring gene male enhanced antigen 1 Neighboring gene protein phosphatase 2, regulatory subunit B', delta Neighboring gene peroxisomal biogenesis factor 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin ligase-substrate adaptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of Cul2-RING ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    kelch domain-containing protein 3
    Names
    protein Peas
    testis intracellular mediator protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163729.2NP_001157201.2  kelch domain-containing protein 3

      See identical proteins and their annotated locations for NP_001157201.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AK079082, AK141673, BY606590, CT030702
      Consensus CDS
      CCDS28834.1
      UniProtKB/Swiss-Prot
      Q8VEM9
      UniProtKB/TrEMBL
      A0A0R4J0W0
      Related
      ENSMUSP00000128271.2, ENSMUST00000165007.9
      Conserved Domains (3) summary
      PLN02153
      Location:74318
      PLN02153; epithiospecifier protein
      sd00038
      Location:128173
      Kelch; KELCH repeat [structural motif]
      pfam13964
      Location:1461
      Kelch_6; Kelch motif
    2. NM_027910.3NP_082186.2  kelch domain-containing protein 3

      See identical proteins and their annotated locations for NP_082186.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AK004964, AK141673, BE945284, CF169399
      Consensus CDS
      CCDS28834.1
      UniProtKB/Swiss-Prot
      Q8VEM9
      UniProtKB/TrEMBL
      A0A0R4J0W0
      Related
      ENSMUSP00000071743.6, ENSMUST00000071841.7
      Conserved Domains (3) summary
      PLN02153
      Location:74318
      PLN02153; epithiospecifier protein
      sd00038
      Location:128173
      Kelch; KELCH repeat [structural motif]
      pfam13964
      Location:1461
      Kelch_6; Kelch motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      46985476..46991856 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524943.5XP_006525006.1  kelch domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006525006.1

      UniProtKB/Swiss-Prot
      Q8VEM9
      UniProtKB/TrEMBL
      A0A0R4J0W0
      Conserved Domains (3) summary
      PLN02153
      Location:74318
      PLN02153; epithiospecifier protein
      sd00038
      Location:128173
      Kelch; KELCH repeat [structural motif]
      pfam13964
      Location:1461
      Kelch_6; Kelch motif
    Support Center