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    Dsn1 DSN1 homolog, MIS12 kinetochore complex component [ Mus musculus (house mouse) ]

    Gene ID: 66934, updated on 23-Jun-2021

    Summary

    Official Symbol
    Dsn1provided by MGI
    Official Full Name
    DSN1 homolog, MIS12 kinetochore complex componentprovided by MGI
    Primary source
    MGI:MGI:1914184
    See related
    Ensembl:ENSMUSG00000027635
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW552447; 1700022L09Rik
    Expression
    Broad expression in liver E14 (RPKM 10.6), CNS E11.5 (RPKM 9.4) and 20 other tissues See more
    Orthologs
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    Genomic context

    See Dsn1 in Genome Data Viewer
    Location:
    2; 2 H1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (156836982..156848995, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (156995062..157007075, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (156820798..156832811, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene N-myc downstream regulated gene 3 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene suppressor of glucose, autophagy associated 1 Neighboring gene TBC/LysM associated domain containing 2 Neighboring gene SAM domain and HD domain, 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic sister chromatid segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of MIS12/MIND type complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    located_in kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nuclear MIS12/MIND complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    kinetochore-associated protein DSN1 homolog
    Names
    DSN1, MIND kinetochore complex component, homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025853.3NP_080129.2  kinetochore-associated protein DSN1 homolog

      See identical proteins and their annotated locations for NP_080129.2

      Status: VALIDATED

      Source sequence(s)
      AK006246, BC046807, CK333431
      Consensus CDS
      CCDS16972.1
      UniProtKB/Swiss-Prot
      Q9CYC5
      Related
      ENSMUSP00000099418.3, ENSMUST00000103129.9
      Conserved Domains (1) summary
      pfam08202
      Location:76346
      MIS13; Mis12-Mtw1 protein family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      156836982..156848995 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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