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    FAM25C family with sequence similarity 25 member C [ Homo sapiens (human) ]

    Gene ID: 644054, updated on 8-Nov-2023

    Summary

    Official Symbol
    FAM25Cprovided by HGNC
    Official Full Name
    family with sequence similarity 25 member Cprovided by HGNC
    Primary source
    HGNC:HGNC:23586
    See related
    Ensembl:ENSG00000276430 AllianceGenome:HGNC:23586
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    bA164N7.4
    Expression
    Biased expression in skin (RPKM 22.8), esophagus (RPKM 4.1) and 2 other tissues See more
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    Genomic context

    Location:
    10q11.22
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (47995322..47999791, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (48844223..48848691, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (49203355..49207825, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene annexin A8 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:47089387-47089886 Neighboring gene uncharacterized LOC124902423 Neighboring gene neuropeptide Y receptor Y4-2 Neighboring gene Sharpr-MPRA regulatory region 8752 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:47136815-47137314 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:47769223-47769865 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:49196054-49197004 Neighboring gene NANOG hESC enhancer GRCh37_chr10:49202415-49202942 Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 12, pseudogene Neighboring gene RNA, 5S ribosomal pseudogene 315

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    protein FAM25C
    Names
    Protein FAM25G
    protein FAM25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001137548.3NP_001131020.1  protein FAM25C

      See identical proteins and their annotated locations for NP_001131020.1

      Status: VALIDATED

      Source sequence(s)
      AC245041, BX093303
      Consensus CDS
      CCDS76299.1
      UniProtKB/Swiss-Prot
      B2RV02, B3EWG3, B3EWG5, B3EWG6, Q5VTM1
      UniProtKB/TrEMBL
      B7ZW47
      Related
      ENSP00000485370.1, ENST00000617224.3
      Conserved Domains (1) summary
      pfam15825
      Location:2488
      FAM25; FAM25 family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      47995322..47999791 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_021160001.1 Reference GRCh38.p14 PATCHES

      Range
      213604..218073 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      48844223..48848691 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)