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    BOLA1 bolA family member 1 [ Homo sapiens (human) ]

    Gene ID: 51027, updated on 5-Mar-2024

    Summary

    Official Symbol
    BOLA1provided by HGNC
    Official Full Name
    bolA family member 1provided by HGNC
    Primary source
    HGNC:HGNC:24263
    See related
    Ensembl:ENSG00000178096 MIM:613181; AllianceGenome:HGNC:24263
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CGI-143
    Summary
    Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in kidney (RPKM 5.6), fat (RPKM 5.6) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    1q21.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (149899568..149900795)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (149012127..149024937)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (149871121..149872348)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1661 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1662 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:149859809-149860403 Neighboring gene H2A clustered histone 21 Neighboring gene uncharacterized LOC124904412 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1664 Neighboring gene synaptic vesicle glycoprotein 2A Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:149881729-149882230 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:149882231-149882730 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1290 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1665 Neighboring gene splicing factor 3b subunit 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC75015

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell redox homeostasis NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in intracellular iron ion homeostasis NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in iron-sulfur cluster assembly NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of iron-sulfur cluster assembly complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    bolA-like protein 1
    Names
    bolA homolog 1
    bolA-like 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001321025.2NP_001307954.1  bolA-like protein 1

      Status: VALIDATED

      Source sequence(s)
      AC239868, AK313014, BQ277416, CB992246
      Consensus CDS
      CCDS939.1
      UniProtKB/Swiss-Prot
      B2R7K2, D3DUZ4, Q5QNY0, Q9Y3E2
      Related
      ENSP00000358149.1, ENST00000369153.2
      Conserved Domains (1) summary
      pfam01722
      Location:40113
      BolA; BolA-like protein
    2. NM_001321026.2NP_001307955.1  bolA-like protein 1

      Status: VALIDATED

      Source sequence(s)
      AC239868, AK313014, BF970430, BQ277416
      Consensus CDS
      CCDS939.1
      UniProtKB/Swiss-Prot
      B2R7K2, D3DUZ4, Q5QNY0, Q9Y3E2
      Related
      ENSP00000358146.1, ENST00000369150.1
      Conserved Domains (1) summary
      pfam01722
      Location:40113
      BolA; BolA-like protein
    3. NM_016074.5NP_057158.1  bolA-like protein 1

      See identical proteins and their annotated locations for NP_057158.1

      Status: VALIDATED

      Source sequence(s)
      AC239868, BQ277416
      Consensus CDS
      CCDS939.1
      UniProtKB/Swiss-Prot
      B2R7K2, D3DUZ4, Q5QNY0, Q9Y3E2
      Related
      ENSP00000358148.5, ENST00000369152.6
      Conserved Domains (1) summary
      pfam01722
      Location:40113
      BolA; BolA-like protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      149899568..149900795
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006711348.4XP_006711411.1  bolA-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006711411.1

      UniProtKB/Swiss-Prot
      B2R7K2, D3DUZ4, Q5QNY0, Q9Y3E2
      Conserved Domains (1) summary
      pfam01722
      Location:40113
      BolA; BolA-like protein

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      149012127..149024937
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054336843.1XP_054192818.1  bolA-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      B2R7K2, D3DUZ4, Q5QNY0, Q9Y3E2
    2. XM_054336845.1XP_054192820.1  bolA-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      B2R7K2, D3DUZ4, Q5QNY0, Q9Y3E2
    3. XM_054336847.1XP_054192822.1  bolA-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      B2R7K2, D3DUZ4, Q5QNY0, Q9Y3E2
    4. XM_054336846.1XP_054192821.1  bolA-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      B2R7K2, D3DUZ4, Q5QNY0, Q9Y3E2
    5. XM_054336844.1XP_054192819.1  bolA-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      B2R7K2, D3DUZ4, Q5QNY0, Q9Y3E2