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    SPDYC speedy/RINGO cell cycle regulator family member C [ Homo sapiens (human) ]

    Gene ID: 387778, updated on 2-May-2024

    Summary

    Official Symbol
    SPDYCprovided by HGNC
    Official Full Name
    speedy/RINGO cell cycle regulator family member Cprovided by HGNC
    Primary source
    HGNC:HGNC:32681
    See related
    Ensembl:ENSG00000204710 MIM:614030; AllianceGenome:HGNC:32681
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    RINGOC; Ringo2; SPDYE4
    Summary
    Enables protein kinase binding activity. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
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    Genomic context

    See SPDYC in Genome Data Viewer
    Location:
    11q13.1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (65170233..65173374)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (65163546..65166687)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (64937704..64940845)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4948 Neighboring gene RNA, U2 small nuclear 23, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3510 Neighboring gene PDCL2 pseudogene 2 Neighboring gene phosphoglycerate mutase 1 pseudogene 8 Neighboring gene hESC enhancers GRCh37_chr11:64949086-64949875 and GRCh37_chr11:64949876-64950664 Neighboring gene CAPN1 antisense RNA 1 Neighboring gene calpain 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    speedy protein C
    Names
    RINGO C
    hSpy/Ringo C
    rapid inducer of G2/M progression in oocytes C
    speedy homolog C

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008778.3NP_001008778.2  speedy protein C

      Status: VALIDATED

      Source sequence(s)
      AP003068
      Consensus CDS
      CCDS31606.2
      UniProtKB/Swiss-Prot
      B2RP32, B7ZMH7, Q5MJ68
      Related
      ENSP00000366390.3, ENST00000377185.3
      Conserved Domains (1) summary
      pfam11357
      Location:38168
      Spy1; Cell cycle regulatory protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      65170233..65173374
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017017710.2XP_016873199.1  speedy protein C isoform X1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      65163546..65166687
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054368737.1XP_054224712.1  speedy protein C isoform X1