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    Rrm2b ribonucleotide reductase M2 B (TP53 inducible) [ Mus musculus (house mouse) ]

    Gene ID: 382985, updated on 28-Aug-2021

    Summary

    Official Symbol
    Rrm2bprovided by MGI
    Official Full Name
    ribonucleotide reductase M2 B (TP53 inducible)provided by MGI
    Primary source
    MGI:MGI:2155865
    See related
    Ensembl:ENSMUSG00000022292
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    p53R2
    Expression
    Ubiquitous expression in bladder adult (RPKM 3.1), frontal lobe adult (RPKM 2.6) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rrm2b in Genome Data Viewer
    Location:
    15; 15 B3.1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (37924196..37961363, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (37923952..37961119, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (37853707..37890810, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S19, pseudogene 5 Neighboring gene predicted gene, 35019 Neighboring gene 60S ribosomal protein L23a pseudogene Neighboring gene predicted gene, 49085 Neighboring gene ubiquitin protein ligase E3 component n-recognin 5 Neighboring gene predicted gene, 22353

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion IC
    Inferred by Curator
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ribonucleoside-diphosphate reductase subunit M2 B
    Names
    TP53-inducible ribonucleotide reductase M2 B
    p53-inducible ribonucleotide reductase small subunit 2-like protein
    NP_001343951.1
    NP_001343952.1
    NP_955770.1
    XP_011243663.1
    XP_036015374.1
    XP_036015375.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357022.1NP_001343951.1  ribonucleoside-diphosphate reductase subunit M2 B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC122291
      Conserved Domains (1) summary
      cl00264
      Location:18337
      Ferritin_like; Ferritin-like superfamily of diiron-containing four-helix-bundle proteins
    2. NM_001357023.1NP_001343952.1  ribonucleoside-diphosphate reductase subunit M2 B isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC122291
      Conserved Domains (1) summary
      cl00264
      Location:1297
      Ferritin_like; Ferritin-like superfamily of diiron-containing four-helix-bundle proteins
    3. NM_199476.1NP_955770.1  ribonucleoside-diphosphate reductase subunit M2 B isoform 1

      See identical proteins and their annotated locations for NP_955770.1

      Status: VALIDATED

      Source sequence(s)
      BC058103
      Consensus CDS
      CCDS27437.1
      UniProtKB/Swiss-Prot
      Q6PEE3
      Related
      ENSMUSP00000022901.10, ENSMUST00000022901.16
      Conserved Domains (1) summary
      cl00264
      Location:32351
      Ferritin_like; Ferritin-like superfamily of diiron-containing four-helix-bundle proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      37924196..37961363 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159481.1XP_036015374.1  ribonucleoside-diphosphate reductase subunit M2 B isoform X2

      Conserved Domains (1) summary
      cl00264
      Location:7203
      Ferritin_like; Ferritin-like superfamily of diiron-containing four-helix-bundle proteins
    2. XM_036159482.1XP_036015375.1  ribonucleoside-diphosphate reductase subunit M2 B isoform X2

      Conserved Domains (1) summary
      cl00264
      Location:7203
      Ferritin_like; Ferritin-like superfamily of diiron-containing four-helix-bundle proteins
    3. XM_011245361.4XP_011243663.1  ribonucleoside-diphosphate reductase subunit M2 B isoform X1

      Conserved Domains (1) summary
      cl00264
      Location:32194
      Ferritin_like; Ferritin-like superfamily of diiron-containing four-helix-bundle proteins

    RNA

    1. XR_004938849.1 RNA Sequence

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