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    Tcaim T cell activation inhibitor, mitochondrial [ Mus musculus (house mouse) ]

    Gene ID: 382117, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tcaimprovided by MGI
    Official Full Name
    T cell activation inhibitor, mitochondrialprovided by MGI
    Primary source
    MGI:MGI:1196217
    See related
    Ensembl:ENSMUSG00000046603
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1129; TOAG-1; D9Ertd402; D9Ertd402e
    Expression
    Ubiquitous expression in heart adult (RPKM 4.1), kidney adult (RPKM 3.1) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Tcaim in Genome Data Viewer
    Location:
    9 F4; 9 73.14 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (122634438..122667989)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (122805513..122838924)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (122714665..122745450)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51699 Neighboring gene testis and ovary specific PAZ domain containing 1 Neighboring gene predicted gene, 35549 Neighboring gene zinc finger protein 445 Neighboring gene zinc finger with KRAB and SCAN domains 7 Neighboring gene zinc finger protein 660

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Clone Names

    • MGC91156

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    T-cell activation inhibitor, mitochondrial
    Names
    tolerance associated gene-1 protein
    tolerance-associated gene 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013405.2NP_001013423.2  T-cell activation inhibitor, mitochondrial

      See identical proteins and their annotated locations for NP_001013423.2

      Status: VALIDATED

      Source sequence(s)
      BB705136, BB849599, BC080690
      Consensus CDS
      CCDS23647.2
      UniProtKB/Swiss-Prot
      Q66JZ4
      UniProtKB/TrEMBL
      G3X983
      Related
      ENSMUSP00000049759.8, ENSMUST00000052740.14
      Conserved Domains (2) summary
      pfam14687
      Location:33139
      DUF4460; Domain of unknown function (DUF4460)
      pfam14688
      Location:200502
      DUF4461; Domain of unknown function (DUF4461)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      122634438..122667989
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512173.5XP_006512236.1  T-cell activation inhibitor, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_006512236.1

      Conserved Domains (2) summary
      pfam14687
      Location:60166
      DUF4460; Domain of unknown function (DUF4460)
      pfam14688
      Location:227529
      DUF4461; Domain of unknown function (DUF4461)
    2. XM_006512174.5XP_006512237.1  T-cell activation inhibitor, mitochondrial isoform X4

      See identical proteins and their annotated locations for XP_006512237.1

      Conserved Domains (1) summary
      pfam14688
      Location:34336
      DUF4461; Domain of unknown function (DUF4461)
    3. XM_006512171.5XP_006512234.1  T-cell activation inhibitor, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_006512234.1

      Conserved Domains (2) summary
      pfam14687
      Location:60166
      DUF4460; Domain of unknown function (DUF4460)
      pfam14688
      Location:227529
      DUF4461; Domain of unknown function (DUF4461)
    4. XM_006512172.5XP_006512235.1  T-cell activation inhibitor, mitochondrial isoform X2

      See identical proteins and their annotated locations for XP_006512235.1

      UniProtKB/TrEMBL
      G3X983
      Conserved Domains (2) summary
      pfam14687
      Location:33139
      DUF4460; Domain of unknown function (DUF4460)
      pfam14688
      Location:200502
      DUF4461; Domain of unknown function (DUF4461)
    5. XM_036155096.1XP_036010989.1  T-cell activation inhibitor, mitochondrial isoform X4

      Conserved Domains (1) summary
      pfam14688
      Location:34336
      DUF4461; Domain of unknown function (DUF4461)
    6. XM_017313450.3XP_017168939.1  T-cell activation inhibitor, mitochondrial isoform X3

      Conserved Domains (1) summary
      pfam14688
      Location:90392
      DUF4461; Domain of unknown function (DUF4461)
    7. XM_030244439.1XP_030100299.1  T-cell activation inhibitor, mitochondrial isoform X4

      Conserved Domains (1) summary
      pfam14688
      Location:34336
      DUF4461; Domain of unknown function (DUF4461)
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