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    FAM89A family with sequence similarity 89 member A [ Homo sapiens (human) ]

    Gene ID: 375061, updated on 5-Mar-2024

    Summary

    Official Symbol
    FAM89Aprovided by HGNC
    Official Full Name
    family with sequence similarity 89 member Aprovided by HGNC
    Primary source
    HGNC:HGNC:25057
    See related
    Ensembl:ENSG00000182118 AllianceGenome:HGNC:25057
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C1orf153
    Expression
    Broad expression in fat (RPKM 41.2), placenta (RPKM 38.9) and 17 other tissues See more
    Orthologs
    NEW
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    Genomic context

    Location:
    1q42.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (231018958..231040254, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (230399853..230421165, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (231154704..231176000, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene MPRA-validated peak762 silencer Neighboring gene tetratricopeptide repeat domain 13 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2720 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1944 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1945 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2721 Neighboring gene ARV1 homolog, fatty acid homeostasis modulator Neighboring gene ring finger protein 4 pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:231174678-231175359 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1947 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1948 Neighboring gene microRNA 1182 Neighboring gene CRISPRi-validated cis-regulatory element chr1.12443 Neighboring gene CRISPRi-validated cis-regulatory element chr1.12444 Neighboring gene CRISPRi-validated cis-regulatory element chr1.12445 Neighboring gene Sharpr-MPRA regulatory region 4964 Neighboring gene CRISPRi-validated cis-regulatory element chr1.12446 Neighboring gene peptidylprolyl isomerase A like 4C pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:231298070-231298704 Neighboring gene NANOG hESC enhancer GRCh37_chr1:231319561-231320089 Neighboring gene tripartite motif containing 67 Neighboring gene TRIM67 antisense RNA 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Phenotypes

    EBI GWAS Catalog

    Description
    Novel genetic variants modify the effect of smoking on carotid plaque burden in Hispanics.
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC15887

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198552.3NP_940954.1  protein FAM89A

      See identical proteins and their annotated locations for NP_940954.1

      Status: VALIDATED

      Source sequence(s)
      AL732414, BC009447, CD365446
      Consensus CDS
      CCDS1590.1
      UniProtKB/Swiss-Prot
      Q96GI7
      Related
      ENSP00000355614.4, ENST00000366654.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      231018958..231040254 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      230399853..230421165 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)