Obox2 oocyte specific homeobox 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Obox2provided by MGI
Official Full Name: oocyte specific homeobox 2provided by MGI
Primary source: MGI:MGI:2149033
See related: Ensembl:ENSMUSG00000074369 AllianceGenome:MGI:2149033
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation; regulation of transcription by RNA polymerase II; and stem cell population maintenance. Is expressed in early conceptus and oocyte. [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward ovary adult (RPKM 3.8) See more
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Genomic context

Location:: 7 A1; 7 8.46 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (15122776..15132470)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (15388851..15398545)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Obox3 (e-PCR), detects polymorphism
- UniSTS:547851

AU024152 (e-PCR)
- UniSTS:179519

Obox1 (e-PCR), detects polymorphism
- UniSTS:239182

C87544 (e-PCR)
- UniSTS:208067

RH127151 (e-PCR)
- UniSTS:208069

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
NOT enables DNA binding	IMP Inferred from Mutant Phenotype more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in stem cell population maintenance	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: inactive oocyte-specific homeobox protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.