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    LKAAEAR1 LKAAEAR motif containing 1 [ Homo sapiens (human) ]

    Gene ID: 198437, updated on 5-Mar-2024

    Summary

    Official Symbol
    LKAAEAR1provided by HGNC
    Official Full Name
    LKAAEAR motif containing 1provided by HGNC
    Primary source
    HGNC:HGNC:33718
    See related
    Ensembl:ENSG00000171695 AllianceGenome:HGNC:33718
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C20orf201
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See LKAAEAR1 in Genome Data Viewer
    Location:
    20q13.33
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (64083376..64084953, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (65903431..65905008, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (62714729..62716306, complement)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:62686363-62687052 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:62687053-62687742 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:62688433-62689122 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:62689123-62689810 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18262 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18263 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13205 Neighboring gene transcription elongation factor A2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18264 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13206 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13207 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:62711846-62712019 Neighboring gene regulator of G protein signaling 19 Neighboring gene microRNA 6813 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13208 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13209 Neighboring gene MPRA-validated peak4324 silencer Neighboring gene opioid related nociceptin receptor 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:62723260-62723993 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:62723994-62724726 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:62732783-62733284 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:62738466-62738966 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:62740950-62741133 Neighboring gene neuropeptides B and W receptor 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:62751601-62752100 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr20:62754467-62755666 Neighboring gene B6.7 minisatellite repeat instability region Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:62768655-62769156 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:62769157-62769656 Neighboring gene uncharacterized LOC105372727 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:62771493-62772406

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    protein LKAAEAR1
    Names
    LKAAEAR motif-containing protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007125.3NP_001007126.1  protein LKAAEAR1 isoform 1

      See identical proteins and their annotated locations for NP_001007126.1

      Status: VALIDATED

      Source sequence(s)
      AL590548
      Consensus CDS
      CCDS33509.1
      UniProtKB/Swiss-Prot
      Q8TD35
      Related
      ENSP00000310801.2, ENST00000308906.6
      Conserved Domains (1) summary
      pfam15478
      Location:40175
      LKAAEAR; Family of unknown function with LKAAEAR motif
    2. NM_001353425.2NP_001340354.1  protein LKAAEAR1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL590548
      Consensus CDS
      CCDS86972.1
      UniProtKB/Swiss-Prot
      Q8N419, Q8TD35, Q8TD36
      Related
      ENSP00000302763.4, ENST00000302096.5
      Conserved Domains (1) summary
      pfam15478
      Location:40175
      LKAAEAR; Family of unknown function with LKAAEAR motif
    3. NM_001386971.1NP_001373900.1  protein LKAAEAR1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL590548
      Consensus CDS
      CCDS86972.1
      UniProtKB/Swiss-Prot
      Q8N419, Q8TD35, Q8TD36
      Conserved Domains (1) summary
      pfam15478
      Location:40175
      LKAAEAR; Family of unknown function with LKAAEAR motif

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

      Range
      64083376..64084953 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024451849.2XP_024307617.1  protein LKAAEAR1 isoform X1

      Conserved Domains (1) summary
      pfam15478
      Location:40175
      LKAAEAR; Family of unknown function with LKAAEAR motif
    2. XM_047439963.1XP_047295919.1  protein LKAAEAR1 isoform X2

      UniProtKB/Swiss-Prot
      Q8N419, Q8TD35, Q8TD36
    3. XM_024451850.2XP_024307618.1  protein LKAAEAR1 isoform X1

      Conserved Domains (1) summary
      pfam15478
      Location:40175
      LKAAEAR; Family of unknown function with LKAAEAR motif

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060944.1 Alternate T2T-CHM13v2.0

      Range
      65903431..65905008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)