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    Pcyt1a phosphate cytidylyltransferase 1, choline, alpha isoform [ Mus musculus (house mouse) ]

    Gene ID: 13026, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pcyt1aprovided by MGI
    Official Full Name
    phosphate cytidylyltransferase 1, choline, alpha isoformprovided by MGI
    Primary source
    MGI:MGI:88557
    See related
    Ensembl:ENSMUSG00000005615
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CTa; Ccta; Ctpc; Ctta; Ctpct; CTalpha; Cctalpha; Cttalpha
    Expression
    Ubiquitous expression in small intestine adult (RPKM 19.0), heart adult (RPKM 14.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pcyt1a in Genome Data Viewer
    Location:
    16 B3; 16 22.69 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (32249739..32293883)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (32430921..32475065)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (32431007..32475151)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene transmembrane 4 L six family member 19 Neighboring gene predicted gene, 20056 Neighboring gene predicted gene, 53948 Neighboring gene dynein light chain Tctex-type 2B Neighboring gene solute carrier family 51, alpha subunit Neighboring gene zinc finger, DHHC domain containing 19

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calmodulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables choline-phosphate cytidylyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables choline-phosphate cytidylyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables choline-phosphate cytidylyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables lipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylcholine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables phosphatidylcholine binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in glycogen granule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    choline-phosphate cytidylyltransferase A
    Names
    CCT A
    CCT-alpha
    CT A
    CTP phosphocholine cytidylyl transferase
    CTP:phosphocholine cytidylyltransferase A
    CTP:phosphocholine cytidylyltransferase alpha
    phosphorylcholine transferase A
    NP_001156631.1
    NP_001156632.1
    NP_034111.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163159.1NP_001156631.1  choline-phosphate cytidylyltransferase A

      See identical proteins and their annotated locations for NP_001156631.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
      Source sequence(s)
      AC087556, AK076050
      Consensus CDS
      CCDS28120.1
      UniProtKB/Swiss-Prot
      P49586
      Related
      ENSMUSP00000130056.2, ENSMUST00000104893.10
      Conserved Domains (1) summary
      cd02174
      Location:75224
      CCT; CTP:phosphocholine cytidylyltransferase
    2. NM_001163160.1NP_001156632.1  choline-phosphate cytidylyltransferase A

      See identical proteins and their annotated locations for NP_001156632.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
      Source sequence(s)
      AC087556, AK076050
      Consensus CDS
      CCDS28120.1
      UniProtKB/Swiss-Prot
      P49586
      Related
      ENSMUSP00000110793.2, ENSMUST00000115140.2
      Conserved Domains (1) summary
      cd02174
      Location:75224
      CCT; CTP:phosphocholine cytidylyltransferase
    3. NM_009981.4NP_034111.1  choline-phosphate cytidylyltransferase A

      See identical proteins and their annotated locations for NP_034111.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
      Source sequence(s)
      AC087556, AK076050, BB642590
      Consensus CDS
      CCDS28120.1
      UniProtKB/Swiss-Prot
      P49586
      Related
      ENSMUSP00000078721.5, ENSMUST00000079791.11
      Conserved Domains (1) summary
      cd02174
      Location:75224
      CCT; CTP:phosphocholine cytidylyltransferase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      32249739..32293883
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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