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    C1orf162 chromosome 1 open reading frame 162 [ Homo sapiens (human) ]

    Gene ID: 128346, updated on 17-Jun-2024

    Summary

    Official Symbol
    C1orf162provided by HGNC
    Official Full Name
    chromosome 1 open reading frame 162provided by HGNC
    Primary source
    HGNC:HGNC:28344
    See related
    Ensembl:ENSG00000143110 AllianceGenome:HGNC:28344
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in spleen (RPKM 7.0), appendix (RPKM 5.5) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See C1orf162 in Genome Data Viewer
    Location:
    1p13.2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (111473984..111478512)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (111481202..111493194)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (112016606..112021134)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1495 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1496 Neighboring gene WD repeat domain 77 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1497 Neighboring gene ATP synthase peripheral stalk-membrane subunit b Neighboring gene transmembrane and immunoglobulin domain containing 3 Neighboring gene RNA, U6 small nuclear 792, pseudogene Neighboring gene adenosine A3 receptor

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    transmembrane protein C1orf162

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001300834.2NP_001287763.1  transmembrane protein C1orf162 isoform 2

      See identical proteins and their annotated locations for NP_001287763.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      BG545926, CA439311
      Consensus CDS
      CCDS72837.1
      UniProtKB/Swiss-Prot
      Q8NEQ5
      Related
      ENSP00000358732.3, ENST00000369718.4
      Conserved Domains (2) summary
      pfam15179
      Location:2162
      Myc_target_1; Myc target protein 1
      cl27601
      Location:46100
      Pectinesterase; Pectinesterase
    2. NM_001300835.2NP_001287764.1  transmembrane protein C1orf162 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
      Source sequence(s)
      AA333542, CA439311, HX785231
    3. NM_174896.4NP_777556.1  transmembrane protein C1orf162 isoform 1

      See identical proteins and their annotated locations for NP_777556.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      BC017973, CA439311
      Consensus CDS
      CCDS837.1
      UniProtKB/Swiss-Prot
      Q5QNZ1, Q8NEQ5
      Related
      ENSP00000344218.5, ENST00000343534.9
      Conserved Domains (1) summary
      pfam15179
      Location:2197
      Myc_target_1; Myc target protein 1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      111473984..111478512
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047446258.1XP_047302214.1  transmembrane protein C1orf162 isoform X1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      111481202..111493194
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054334454.1XP_054190429.1  transmembrane protein C1orf162 isoform X2

      UniProtKB/Swiss-Prot
      Q5QNZ1, Q8NEQ5
    2. XM_054334455.1XP_054190430.1  transmembrane protein C1orf162 isoform X3

    3. XM_054334456.1XP_054190431.1  transmembrane protein C1orf162 isoform X4

    4. XM_054334457.1XP_054190432.1  transmembrane protein C1orf162 isoform X1