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    Cdc42ep2 CDC42 effector protein (Rho GTPase binding) 2 [ Mus musculus (house mouse) ]

    Gene ID: 104252, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cdc42ep2provided by MGI
    Official Full Name
    CDC42 effector protein (Rho GTPase binding) 2provided by MGI
    Primary source
    MGI:MGI:1929744
    See related
    Ensembl:ENSMUSG00000045664
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bor; Cep; Cep2; Borg1; D19Bwg1013e; 1110008C05Rik
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 26.1), large intestine adult (RPKM 24.0) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Cdc42ep2 in Genome Data Viewer
    Location:
    19 A; 19 4.34 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5967584..5974844, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5917556..5924816, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (5917561..5918995, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene D4, zinc and double PHD fingers family 2 Neighboring gene predicted gene, 42067 Neighboring gene polymerase (DNA directed), alpha 2 Neighboring gene solute carrier family 22 (organic anion transporter), member 20 Neighboring gene predicted gene, 31719

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables opioid peptide activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in phagocytic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cdc42 effector protein 2
    Names
    binder of Rho GTPases 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026772.2NP_081048.1  cdc42 effector protein 2

      See identical proteins and their annotated locations for NP_081048.1

      Status: VALIDATED

      Source sequence(s)
      AC127271, AC131692, BB842420
      Consensus CDS
      CCDS29484.1
      UniProtKB/Swiss-Prot
      Q8JZX9
      Related
      ENSMUSP00000059883.5, ENSMUST00000055458.6
      Conserved Domains (2) summary
      pfam00786
      Location:2984
      PBD; P21-Rho-binding domain
      pfam14957
      Location:103204
      BORG_CEP; Cdc42 effector

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      5967584..5974844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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